有机磷杀虫剂乐果果对成年雄性大鼠生殖系统和生育能力的影响

F. Ngoula, P. Watcho, A. Kenfack, Joseph N’zouk Manga, H. Defang, Kamtchouing Pierre, Tchoumboué Joseph
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引用次数: 22

摘要

农药是最具潜在危害的化学物质之一,以一种计划外的方式释放到环境中。在许多国家,乐果作为一种强效农药被广泛使用,并已被证明会对健康产生一些不利影响。本研究探讨了有机磷杀虫剂乐果果对雄性大鼠生殖系统和生育能力的影响及其可能的作用机制。将24只成年Wistar雄性大鼠分为4组,每组6只,分别饲喂0、3.66、5.50和11 mg kg-1体重的乐果90 d。在80天的治疗中,每只雄性被允许与两只初产周期雌性交配。结果显示显著降低(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EFFECT OF DIMETHOATE (AN ORGANOPHOSPHATE INSECTICIDE) ON THE REPRODUCTIVE SYSTEM AND FERTILITY OF ADULT MALE RAT
The pesticides are one of the most potentially harmful chemicals liberated in the environment in an unplanned manner. Dimethoate is widely used as a potent pesticide in many countries and has been shown to produce some adverse health effects. In the present study, we investigated the effect of dimethoate (an organophosphate insecticide) on the reproductive system and fertility of male rats and the possible mechanism underlining its action. Twenty four adult Wistar male rats were divided into 4 groups of 6 animals per group and force-fed with 0, 3.66, 5.50 and 11 mg kg-1 body weight of dimethoate for 90 days. At 80 days of treatment, each males was allows to mate with two primiparous cyclic females. The results showed a significant decrease (p
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