Titanium Toxicity and Allergy: A Commentary with Focus on Titanium Spectacle Frames

Considered as an inert, extremely resistant, and biocompatible metal, titanium has prevailed for years, as the most valuable material used for the manufacture of dental implants and orthopedic prosthetics. However, titanium is not infallible, as it has been subject to corrosion and to subsequent titanium toxicity, hypersensitivity, and probably also to a form of autoimmunity. Evidence of failure of the contraption, though, is relatively rare. While commenting on its medical advantages and its setbacks, we discuss the rare use of the metal in the spectacles industry and some of its exceptional, related complications.