{"title":"拉科沙胺和替扎尼定联合治疗癫痫和多发性硬化症引起的高级别房室传导阻滞","authors":"S. Kilic, U. Canpolat","doi":"10.32552/2022.actamedica.779","DOIUrl":null,"url":null,"abstract":"Drug-induced atrioventricular (AV) block can be caused by cardiac and non-cardiac medications. The clinical condition may be temporary, persistent, or recurrent. However, there is no standard approach for management and follow-up of patients with drug-induced AV block. Herein, we presented a patient with the diagnosis of epilepsy and multiple sclerosis who admitted to emergency room with epileptic seizure. Temporary advanced AV block was observed on admission and during in-hospital follow-up which was thought to be caused by lacosamide and tizanidine medications and improved after drug discontinuation.","PeriodicalId":50891,"journal":{"name":"Acta Medica Mediterranea","volume":"1 1","pages":""},"PeriodicalIF":0.3000,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"High-grade Atrioventricular Block Due to Lacosamide and Tizanidine Combination Therapy for Epilepsy and Multiple Sclerosis\",\"authors\":\"S. Kilic, U. Canpolat\",\"doi\":\"10.32552/2022.actamedica.779\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Drug-induced atrioventricular (AV) block can be caused by cardiac and non-cardiac medications. The clinical condition may be temporary, persistent, or recurrent. However, there is no standard approach for management and follow-up of patients with drug-induced AV block. Herein, we presented a patient with the diagnosis of epilepsy and multiple sclerosis who admitted to emergency room with epileptic seizure. Temporary advanced AV block was observed on admission and during in-hospital follow-up which was thought to be caused by lacosamide and tizanidine medications and improved after drug discontinuation.\",\"PeriodicalId\":50891,\"journal\":{\"name\":\"Acta Medica Mediterranea\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2022-11-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Medica Mediterranea\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.32552/2022.actamedica.779\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Medica Mediterranea","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.32552/2022.actamedica.779","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
High-grade Atrioventricular Block Due to Lacosamide and Tizanidine Combination Therapy for Epilepsy and Multiple Sclerosis
Drug-induced atrioventricular (AV) block can be caused by cardiac and non-cardiac medications. The clinical condition may be temporary, persistent, or recurrent. However, there is no standard approach for management and follow-up of patients with drug-induced AV block. Herein, we presented a patient with the diagnosis of epilepsy and multiple sclerosis who admitted to emergency room with epileptic seizure. Temporary advanced AV block was observed on admission and during in-hospital follow-up which was thought to be caused by lacosamide and tizanidine medications and improved after drug discontinuation.
期刊介绍:
Acta Medica Mediterranea is an indipendent, international, English-language, peer-reviewed journal, online and open-access, designed for internists and phisicians.
The journal publishes a variety of manuscript types, including review articles, original research, case reports and letters to the editor.