胆总管肉瘤样癌的快速进展

Moon Jin Kim, Jun Suh Lee, Yu Mi Kim, Soyeon An, Y. Yoon
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引用次数: 1

摘要

中央商务区中部狭窄(图1)。远端胆管刷细胞学涂片显示非典型细胞,提示腺癌。我们没有做肝脏磁共振成像,因为CT上没有肝转移的嫌疑。术前影像学分期为T2或T3N0M0。由于总胆管肉瘤样癌(CBD)很少报道,其临床病程和术后预后尚不清楚。我们报告一例因肿瘤快速进展而在手术后1个月内死亡的患者。65岁女性腹痛伴黄疸。她被诊断为CBD癌,并接受了胰十二指肠切除术。病理检查显示为肉瘤样癌。术后无并发症,但术后7天计算机断层扫描发现多发肝转移。术后第14天患者主诉腹痛,黄疸伴肝酶升高。她的一般情况越来越糟,手术后23天死于肝功能衰竭。我们报告一例进展非常迅速的CBD肉瘤样癌。需要进一步的研究和病例报告,以建立适当的诊断和治疗工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rapid progression of sarcomatoid carcinoma of the common bile duct
narrowing in mid CBD (Fig. 1). Brush cytology smears from the distal bile duct showed atypical cell, suggesting adenocarcinoma. We did not perform liver mag-netic resonance imaging because there was no suspicion of liver metastasis on CT. Preoperative imaging stage was T2 or T3N0M0. Since sarcomatoid carcinoma in the common bile duct (CBD) is rarely reported, the clinical course and prognosis after surgery are unclear. We report a case of a patient who died within 1 month after surgery due to rapid tumor progression. A 65-year-old woman had abdominal pain with jaundice. She was diagnosed with CBD cancer and underwent pancreatoduodenectomy. Pathologic examination revealed sarcomatoid carcinoma. There was no postoperative complication, but multiple liver metastasis was diagnosed on computed tomography at 7 days after surgery. Also, the patient complained of abdominal pain and had jaundice with elevated liver enzyme on the 14th postoperative day. Her general condition was getting worse and she died of hepatic failure 23 days after surgery. We report a case of sarcomatoid carcinoma of the CBD that progressed very rapidly. Further research and case reports are needed to establish proper diagnostic and treatment tools.
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