糖尿病患者细菌性尿路感染及多重耐药菌的评价

Girish Narayanaswamy, Reenu S.P, R. Kushwaha
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摘要

膀胱感染是各年龄段糖尿病患者的常见病。急性膀胱炎在糖尿病患者中发病率较高。尿路感染是世界范围内最常见和最广泛的感染。尿路感染在糖尿病患者中发生率最高。糖尿病(DM)是一组以高血糖为特征的代谢障碍,由胰岛素分泌、胰岛素作用或两者的缺陷引起。这是一种常见的疾病,在很多方面影响着健康,也是世界范围内的主要疾病之一。尿路感染医疗辅助实验对尿培养和敏感性的执行较少。本研究旨在了解尿路感染的细菌性尿路感染发生情况、多药耐药菌、健康风险及抗菌药物使用情况。假设糖尿病和非糖尿病无症状尿路感染患者的尿路病原体谱和抗生素耐药模式。该研究在班加罗尔Whitefield的Vydehi医学科学和研究中心(VIMS & RC)进行了为期6个月(2022年4月至9月)的研究。研究对象包括18岁以上的糖尿病患者和非糖尿病患者,这些患者来自门诊,同时也在VIMS & RC的普通内科住院。收集门诊和住院患者糖尿病和非糖尿病患者尿液样本247份,并在微生物实验室进行处理。根据临床及实验室标准学会的原则,收集及分析尿样。使用VITEK 2全自动系统分析仪测定抗菌药物敏感性。糖尿病合并细菌尿中分离出多重耐药菌48株(53%)。非糖尿病合并菌尿的细菌分离株29株(17%)。而且经常被孤立。革兰氏阴性菌对阿米卡星、呋喃妥因、头孢曲松、克拉维酸、头孢匹罗等多种药物高度耐药,且对可及抗生素的耐药性日益增强。是最常见的分离微生物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bacterial urinary tract infection in diabetes patients and evaluation for multidrug resistant organisms
Bladder infection exists as frequently occurring infectious disease in diabetic mellitus of all distinct age groups. Acute cystitis is recognised as higher frequency in person with diabetes. Urinary Tract infection is most familiar and widespread infection in world-wide. The frequency of urinary tract infection is at peak in patients with diabetic mellitus. Diabetic mellitus (DM) is a group of metabolic impairment characterised by hyperglycaemia resulting from defects in insulin secretion, insulin action or both. It’s a common disease that affects health in many ways and relevant problems one of the leading illness world-wide. Urinary tract infection medical aid experimental is less execution of urine culture and sensitivity. In the present study designed to find out occurrence of bacterial urinary tract infection, Multidrug resistant organisms, health risk and antimicrobial drug medication for UTI’s. To hypothesize the spectrum of uropathogens and the profile of antibiotic resistance pattern in both diabetic and non-diabetic patient with asymptomatic urinary tract infection.The research study was performed for the duration of 6 Months (April-September 2022) in Vydehi Institute of medical science and research centre (VIMS & RC) Whitefield Bangalore. Diabeticas well as non-diabetic patientsabove 18 years of age, from OPD and also admitted in General medicine department of VIMS & RC was considered. A total of 247 diabetic and non-diabetic urine samples from outpatients and inpatients was collected and processed in the microbiology laboratory. In accordance to principle of Clinical and Laboratory Standards Institute, the urine samples was collected and analysed. VITEK 2 Automated system analyser was used to determine Antimicrobial Sensitivity. Bacterial Multidrug Resistant Organism isolates in diabetes mellitus with bacteriuria is 48 (53%). Bacterial isolates in non-diabetic mellitus with bacteriuria is 29 (17%). and is frequently isolated. Gram-negative bacteria are highly resistant to multiple drugs like, Amikacin, Nitrofurantoin, Ceftriaxone, Clavulanic acid, Cefpirome, etc moreover increasingly resistant accessible antibiotics. and was the most familiar isolated microorganisms.
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