巧妙漱口:肉豆蔻漱口水

G. Shetty, Samhita Dabak Pg Student, Dipika K. Mitra Prof Hod, Rohit Shah Reader, Silvia Rodrigues Reader, Saurabh Prithyani
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摘要

本研究旨在评估肉豆蔻漱口水的抗牙菌斑作用。研究了肉豆寇漱口水对中间普雷沃菌(Pi)、牙龈卟啉单胞菌(Pg)和放线菌聚集菌(Aa)的体外抗菌性能。材料与方法对肉豆蔻漱口水进行皮、Pg、Aa的体外抑菌试验。30名年龄在21- 23岁(平均年龄22岁)的牙周健康受试者参加了为期4天的横截面牙菌斑再生长研究,并分为两组,每组分配一种漱口水。漱口水被标记为A和b。漱口水A是肉豆蔻漱口水;漱口水B为市售0.2%洗必泰漱口水。建议受试者避免使用任何机械口腔卫生技术。第1、5天检查斑块指数(PI)。洗脱期两周后,更换漱口水,再次进行交叉临床试验,并在第1天和第5天进行斑块评分。结果A、B组大鼠血清spi在试验第1 ~第5天显著升高(P < 0.01)。在组间比较中,肉豆蔻漱口水与氯己定漱口水几乎相当。然而,氯己定显示出更好的抗斑块活性。体外实验表明,0.01%肉豆蔻漱口水对Pi、Pg、Aa均有较好的抑制作用。结论:肉豆蔻漱口水虽不如氯己定漱口水有效,但仍是一种有效的牙菌斑抑制剂。对于喜欢天然产品的患者,它可以作为一个很好的选择。关键词抗牙菌斑;漱口水;肉豆蔻
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rinse Smart: Nutmeg Mouthwash
Brief Background This study was undertaken to assess the anti-plaque efficacy of Nutmeg mouthwash. The antibacterial properties of nutmeg mouthwash against Prevotella intermedia (Pi), Porphyromonas gingivalis (Pg), and Aggregatibacter actinomycetemcomitans (Aa) in vitro were also assessed. Materials and Methods In vitro testing of Nutmeg mouthwash against Pi, Pg, and Aa was carried out. Thirty periodontally healthy subjects between the age group of 21- 23 years (mean age 22 years) were enrolled in the cross sectional 4-day plaque re-growth study and were divided into two groups and assigned one mouthwash for each group. Mouthwashes were labelled as A and B. Mouthwash A was a Nutmeg mouthwash; Mouthwash B was commercially available 0.2% Chlorhexidine mouthwash. Subjects were advised to refrain from any kind of mechanical oral hygiene techniques. Plaque index (PI) was checked on day 1 and 5. After a washout period of two weeks, the mouthwashes were switched and cross-over clinical trial was again carried out and plaque scores were taken on day 1 and 5. Results Pi significantly increased from day 1 to day 5 (P < 0.01) in Groups A and B during all the trails. In inter-group comparison, Nutmeg mouthwash was almost comparable to Chlorhexidine mouthwash. However, chlorhexidine showed superior anti-plaque activity. In vitro test, showed Nutmeg mouthwash (0.01%) was effective against Pi, Pg, and Aa. Conclusion: Nutmeg mouthwash was found to be potent plaque inhibitor although less efficacous than Chlorhexidine mouthwash. It can serve as a good alternative for the patients who prefer natural products. Key words Anti-plaque, mouthwash, Nutmeg
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