Novel Approach for Producing Pharmaceuticals in Layer by Layer Fashion: Additive Manufacturing

drug three ABSTRACT: A novel approach for producing pharmaceuticals from digital designs, in a layer-by-layer fashion is 3D printing. It has been acclaimed as a disruptive technology having the potential to make a paradigm shift in the conventional manufacturing of pharmaceuticals products which involves various unit operations like milling, mixing, granulation, drying and compression. It results in final products of different qualities. The quality of the product is influenced by loading of the drug, release of the drug, stability of the drug and stability of pharmaceutical dosage form. FDA approved 3D printed drug is creating a novel era in pharmaceutical manufacturing. To overcome some of the challenges associated with conventional pharmaceutical unit operations, 3D printing is gaining more attention in the manufacture of pharmaceuticals in the future. 3D printing is capable of overcoming the difficulties relating to the drug delivery of peptides, potent drugs, water-soluble drugs, and the release of multi-drugs. On the other hand we can prepare patient specific or patient tailored medications on patient demand thus making safe administration of drug without any side effects or adverse drug effects. Nevertheless,certain limitations are there in terms of regulatory aspects hindering the launch of 3DP products into the market. © 2020 iGlobal Research and Publishing Foundation.