基于诱导多能干细胞(ipsc)的治疗方法的最新进展

Journal of stem cell research & therapeutics Pub Date : 2017-09-14 DOI:10.15406/JSRT.2017.03.00100

Santosh Gupta, Vineeta Sharma, R. Verma

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引用次数: 5

摘要

缩写:iPSC，诱导多能干细胞;胚胎干细胞;体细胞核移植;转录因子;Sox2，性别决定区y-box 2;Klf4, krueppel-like factor 4;Utf1，未分化胚胎细胞转录因子1;Sall4，盐样蛋白4;端粒酶，逆转录酶;HAT，组蛋白乙酰转移酶;creb结合蛋白;间充质干细胞;PDAC，胰腺癌细胞模型;BMEC，脑微血管内皮细胞;亨廷顿舞蹈症

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Recent advances in induced pluripotent stem cell (ipsc) based therapeutics

Abbreviations: iPSC, induced pluripotent stem cells; ESC, embryonic stem cells; SCNT, somatic cell nuclear transfer; TFs, transcription factors; Sox2, sex determining region y-box 2; Klf4, krueppel-like factor 4; Utf1, undifferentiated embryonic cell transcription factor 1; Sall4, sal-like protein 4; hTERT, telomerase reverse transcriptase; HAT, histone acetyltransferase; CBP, creb binding protein; MSC, mesenchymal stem cells; PDAC, pancreatic cancer cell model; BMEC, brain micro vascular endothelial cells; HD, huntington disease

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Journal of stem cell research & therapeutics

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