使用血管内加温导管的重度烧伤患者的静脉血栓栓塞:回顾性队列研究

IF 1 Q4 CRITICAL CARE MEDICINE
Isabella Reid, Hadley Bortz, Aidan Burrell, Dashiell Gantner, Samara Rosenblum, Heather Cleland
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引用次数: 0

摘要

背景:大面积烧伤后使用血管内加温导管可有效维持体温正常,但使用时可能会出现并发症。本研究旨在确定使用血管内加温导管的患者中有多大比例发生了可能与导管相关的静脉血栓栓塞(VTE),并找出诱发风险因素。方法:这是一项回顾性队列研究:这是一项回顾性队列研究,研究对象是2013年1月至2018年7月入住维多利亚州成人烧伤服务机构的重度烧伤(TBSA>20%)患者,这些患者都安装了ICYTM血管内加温导管。一名作者通过手动搜索患者的医疗记录来确定导管插入情况和其他细节,而 VTE 的发生率则由编码部门从中央数据库中确定。结果:40 名患者在研究期间插入了血管内加温导管。导管组中发生 VTE 的患者人数为 8 人(20%),其中 4 人(10%)可能因解剖位置而与导管有关。在这四例可能与导管相关的 VTE 病例中,还发现了其他可预防的 VTE 风险因素,包括预防性抗凝不达标(2 例)、导管持续时间过长(1 例)和血液浓缩时间过长(2 例)。结论我们发现,在使用血管内加温装置的重度烧伤患者中,有 20% 存在严重的 VTE;但其中只有一半可能与导管有关。在使用血管内加温装置之前,应对每位患者进行仔细评估,平衡风险与收益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Venous Thromboembolism in Severe Burns Patients with Intravascular Warming Catheter: A Retrospective Cohort Study.

Background: Use of intravascular warming catheters following major burns has been shown to be effective to maintain normothermia, but their use may be associated with complications. The aim of this study was to determine what proportion of patients with an intravascular warming catheter developed a potentially catheter-related venous thromboembolism (VTE) and to identify contributing risk factors. Methods: This was a retrospective cohort study of patients admitted to the Victorian Adult Burns Service January 2013 to July 2018 with major burns (TBSA > 20%) who had an ICYTM intravascular warming catheter. Warming catheter insertion and other details were identified with a manual search of the patients' medical records by a single author while incidence of VTE was determined by the coding department from a central database. Results: Forty patients had an intravascular warming catheter inserted during the study period. The number of patients in the catheter group that sustained a VTE was eight (20%), of which four (10%) could have been catheter-related due to the anatomical location. In the cases of the four potentially catheter-related VTE, other preventable VTE risk factors including suboptimal prophylactic anticoagulation (n = 2), prolonged catheter duration (n = 1) and prolonged haemoconcentration (n = 2) were identified. Conclusions: We found 20% of major burns patients with an intravascular warming device had significant VTE; however, only half of these may have been related to the catheter. A careful assessment for each patient that balances risks and benefits should be undertaken prior to using intravascular warming devices.

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