黄芩素对帕金森病患者的神经保护作用

Yu Xin
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引用次数: 10

摘要

黄芩素是一种从中药黄芩干根中提取的类黄酮化合物,作为抗氧化剂和抗炎剂已被广泛应用。随着对黄芩素作用机制的不断研究,近年来发现黄芩素对帕金森病等神经退行性疾病具有一定的神经保护作用和改善临床症状的作用。近年来的研究表明,其神经保护作用与抗炎、抗氧化应激、保护线粒体、抑制谷氨酸神经毒性、促进神经生长、抑制α -突触核蛋白聚集活性等功能密切相关。本文就黄芩素在帕金森病中的神经保护作用进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Neuroprotective effect of baicalein in patients with Parkinson's disease].
: Baicalein, a flavonoid compound extracted from dried roots of traditional Chinese medicine Scutellaria baicalensis, has been widely applied as an antioxidant and anti-inflammatory agent. With continuous studies on its mechanisms, recent findings suggest that baicalein has some effect on neuroprotection and improvement of clinical symptoms in neurodegenerative diseases such as Parkinson's disease. Recent studies showed that its neuroprotective efficacy is closely related to such functions as antiinflammatory, antioxidative stress, protecting chondriosome, inhibiting glutamate neurotoxicity, promoting nerve growth and inhibiting alpha-synuclein protein-aggregate activities. The aim of this article is to summarize the neuroprotective effects of baicalein in Parkinson's disease.
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