基于神经网络和支持向量机的动态磁共振成像乳腺癌特征选择与分类

Farzaneh Keyvanfard, M. A. Shoorehdeli, M. Teshnehlab
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引用次数: 16

摘要

由于其高灵敏度,动态磁共振成像(MRI)已成为一种强大的乳腺癌诊断工具,并在传统乳房x光检查结果不明确的情况下发挥了作用[1]。在临床环境中,人工神经网络已被广泛应用于乳腺癌诊断,它根据定义的标准对不同特征进行主观印象。本研究将基于人工神经网络(ANN)和支持向量机(SVM)的特征选择和分类方法应用于动态磁共振成像(MRI)上的乳腺癌分类。指定了包含良、恶性病变的数据库,以选择特征并使用所提出的方法进行分类。该数据收集于2004年至2006年。采用前向选择方法寻找最佳特征进行分类。此外,在共112例经组织病理学证实的乳腺病变上,提出了MLP、PNN、GRNN、RBF等神经网络分类器,将乳腺病变分为良、恶性两组。支持向量机也被认为是分类器。通过考虑四重交叉验证得到训练分类器和召回分类器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feature Selection and Classification of Breast Cancer on Dynamic Magnetic Resonance Imaging Using ANN and SVM
Breast cancer Dynamic magnetic resonance imaging (MRI) has emerged as a powerful diagnostic tool for breast cancer detection due to its high sensitivity and has established a role where findings from conventional mammography techniques are equivocal[1]. In the clinical setting, the ANN has been widely applied in breast cancer diagnosis using a subjective impression of different features based on defined criteria. In this study, feature selection and classification methods based on Artificial Neural Network (ANN) and Support Vector Machine (SVM) are applied to classify breast cancer on dynamic Magnetic Resonance Imaging (MRI). The database including benign and malignant lesions is specified to select the features and classify with proposed methods. It was collected from 2004 to 2006. A forward selection method is applied to find the best features for classification. Moreover, several neural networks classifiers like MLP, PNN, GRNN and RBF has been presented on a total of 112 histopathologically verified breast lesions to classify into benign and malignant groups. Also support vector machine have been considered as classifiers. Training and recalling classifiers are obtained with considering four-fold cross validation.
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