基于碳纳米管纳米自组装的高分辨率乙酰胆碱生物传感器

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS) Pub Date : 2007-01-01 DOI:10.1109/MEMSYS.2007.4433151

W. Xue, T. Cui

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引用次数: 4

摘要

我们提出了一种基于碳纳米管薄膜的器件作为高分辨率乙酰胆碱传感器。碳纳米管薄膜和乙酰胆碱酯酶薄膜分别在硅衬底上自组装为导电层和传感层。这两种薄膜都是用一层一层的自组装工艺沉积的。乙酰胆碱溶液中产生的氢离子改变了碳纳米管薄膜的电导。该装置的分辨率测量为100pm。碳纳米管生物传感器具有分辨率高、体积小、成本低等特点，在医学研究和临床诊断方面具有巨大的应用潜力。

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A high-resolution amperometric acetylcholine biosensor based on nano self-assembly of carbon nanotubes

We present a carbon nanotube thin film based device as a high-resolution acetylcholine sensor. Carbon nanotube and acetylcholinesterase thin films are self-assembled on a silicon substrate as conducting and sensing layers, respectively. Both films are deposited using layer-by-layer self-assembly process. The conductance of the carbon nanotube film is changed due to the generated hydrogen ions in the acetylcholine solution. The resolution of the device is measured as 100 pM. Due to its high resolution, small size, and low cost, the carbon nanotube biosensor has tremendous potential for applications to medical research and clinical diagnosis.

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来源期刊

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)

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