port-catheter系统在耐多药结核病和延长耐药结核病患者强化静脉化疗中的安全性和有效性

Y. Senko
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引用次数: 0

摘要

背景。豫港(“豫药”)是一种长期输液的植入系统。该系统允许多次进入血管进行药物、液体和营养液的肠外给药。目标。描述port-catheter系统在耐多药结核病(TB)和扩展耐药结核病患者强化静脉化疗中的安全性和有效性。材料和方法。对这一问题的文献进行分析。结果和讨论。在长期输液治疗或化疗的情况下,以及使用刺激静脉的药物时,需要延长静脉通路。常规的血管通路方法有许多缺点:每次注射时,系统的针头都会损坏血管;输液套管应每3-5天更换一次;中心静脉导管不能永久放置(平均放置1周)。因此,由钛金属端口和血管导管组成的端口系统一直被用于长期静脉通路。安装端口系统时,导管在静脉内,端口在皮肤下,针头被取出。Yu-Port系统的优点包括大硅胶膜,流体流速为5ml /s,与磁共振成像兼容,不含乳胶和聚氯乙烯。游戏端口包包含安装说明和所有必要的工具。硅胶膜允许重复穿孔只有用特殊的玉港针或包括针。穿刺后,膜被收紧,因为由于特殊的锐化针不会撕裂膜材料,而是将其推开。颈静脉或锁骨下通道最常用于安装端口。在化疗中使用port系统的优点包括创伤小,无痛注射,无不适,易于给药和抽血分析,发生静脉炎的风险较低,使用时间长(数年)。我们自己对port系统的经验(2019-2020年的56例患者)显示,由于副作用而过早终止治疗的人数明显少于标准输注治疗组(12.50%对22.6%)。结论:1。端口系统由钛端口和血管导管组成,长期用于长期静脉通路。2. 在化疗中使用port系统的优点包括无痛注射、无不适、易于给药和抽血分析、静脉炎风险低、使用时间长。3.对于需要长期或多组分化疗的患者,例如耐多药结核病患者,建议使用port系统。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Safety and efficacy of the port-catheter systems during intensive intravenous chemotherapy in patients with multidrug-resistant tuberculosis and tuberculosis with extended resistance
Background. Yu-Port (“Yuria-Pharm”) is an implanted system for long-term infusions. This system allows multiple access to vessels for parenteral administration of drugs, fluids and nutrient solutions. Objective. To describe the safety and efficacy of the port-catheter systems during intensive intravenous chemotherapy in patients with multidrug-resistant tuberculosis (TB) and TB with extended resistance. Materials and methods. Analysis of the literature on this issue. Results and discussion. Prolonged venous access is required in case of long-term infusion therapy or chemotherapy, as well as with the use of drugs that irritate the veins. Routine methods of vascular access have a number of disadvantages: the needle of the system damages the vessel with each injection; infusion cannula should be replaced every 3-5 days; the central venous catheter cannot be installed permanently (on average, for 1 week). Therefore, port systems consisting of a titanium port and a vascular catheter have long been used for long-term venous access. When installing the port system, the catheter is in the vein, the port is under the skin, and the needle is brought out. The advantages of the Yu-Port system include a large silicone membrane, fluid flow rate of 5 ml/s, compatibility with magnetic resonance imaging, and the absence of latex and polyvinyl chloride. The Yu-Port package contains installation instructions and all the necessary tools. The silicone membrane allows repeated piercing only with a special Yu-Port needle or the included needle. After the puncture, the membrane is tightened, because due to a special sharpening needle does not tear the membrane material, but pushes it apart. Jugular or subclavian access is most often used to install ports. The advantages of using port systems in chemotherapy include low traumaticity, painless injections, no discomfort, ease of drug administration and blood sampling for analysis, lower risk of developing phlebitis, long use duration (several years). Our own experience with port systems (56 patients in 2019-2020) showed significantly fewer premature treatment terminations due to side effects than in the group of standard infusion therapy (12.50 % vs. 22.6 %). Conclusions. 1. Port systems consisting of a titanium port and a vascular catheter have long been used for long-term venous access. 2. The advantages of using port systems in chemotherapy include painless injections, no discomfort, ease of drug administration and blood sampling for analysis, lower risk of phlebitis, long use duration. 3. In patients who need long-term or multicomponent chemotherapy, for example, in multidrug-resistant TB, it is advisable to use port systems.
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