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JURNAL BIOMEDIK (JBM) Pub Date : 2018-07-11 DOI:10.35790/JBM.10.2.2018.20090

Edi Suyanto, E. Prasetyo, M. C. Oley

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引用次数: 0

摘要

摘要:本研究旨在证明重型颅脑损伤(TBI)患者血清IL-10水平和外周血白细胞水平的升高，以及两者之间的相关性。这是一项分析性相关研究。所有患者IL-10水平均高于正常值(18 pg/ml)。3例患者血液白细胞水平正常。采用简单线性回归分析和Pearson相关系数分析检验IL-10与血白细胞水平的相关性，r = 0.045, P = 0.426(>0.05)。这些结果表明IL-10与白细胞水平呈正相关，但无统计学意义。结论:白细胞介素-10在重型颅脑损伤后持续升高，是一种比外周白细胞水平更好的生物标志物。关键词:白细胞介素-10;白细胞介素-10;白细胞介素-10;白细胞介素-10;Jenis penelitian是一名分析师。Hasil penelitian mendapatkan 20 pasen dengan COT berberia 16-65 tahun。Semua pasien memperlihatkan kadar Il-10数据正常(18 pg/ml)。Terdapat 3 pasen dengan kadar leukois dalam batas normal Hubungan antara IL-10 danleukois diuji dengan analysis回归线性分析Pearson danmendapatkan r = 0.045 dengan P = 0.026。白细胞介素-10 (IL-10)与白化病(IL-10)的相关性比较，差异有统计学意义(P = 0.0426 > 0.05)。类人猿:IL-10 secara一致脑膜kat setelah COT和sebagai生物标志物COT yang lebih baik daripada白斑。Kata kunci: IL-10，白细胞，COT

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Hubungan Kadar Interleukin-10 Serum dan Kadar Leukosit Darah Perifer pada Pasien Cedera Otak Berat Akibat Trauma

Abstract: This study was aimed to prove that in severe traumatic brain injury (TBI) there was an elevation in serum IL-10 level as well as in peripheral blood leukocyte level, and a correlation between both of them. This was an analytical correlational study. All patients had IL-10 level above normal value (18 pg/ml). There were three patients with normal blood leukocyte level. The correlation between IL-10 and blood leukocyte level was tested by using simple linear regression analysis and Pearson correlation coefficient analysis which obtained r = 0.045 with a P of 0.426 (>0.05). These results indicated a positive relationship between IL-10 and leukocytes levels, but not statistically significant. Conclusion: Interleukin-10 was consistantly elevated following severe traumatic brain injury and was a better TBI biomarker than the peripheral leukocyte level.Keywords: IL-10, leukocytes, TBIAbstrak: Penelitian ini bertujuan untuk membuktikan bahwa pada cedera otak akibat trauma (COT) berat terdapat peningkatan kadar serum IL-10 dan kadar leukosit darah perifer serta korelasi antara keduanya. Jenis penelitian ini ialah analitik korelasional. Hasil penelitian mendapatkan 20 pasien dengan COT berat berusia 16-65 tahun. Semua pasien memperlihatkan kadar Il-10 di atas nilai normal (18 pg/ml). Terdapat 3 pasien dengan kadar leukosit dalam batas normal Hubungan antara IL-10 dan leukosit diuji dengan analisis regresi linier sederhana dan analisis koefisien korelasi Pearson dan mendapatkan r = 0,045 dengan P = 0,426. Hasil ini menunjukkan hubungan positif antara IL-10 dan leukosit, tetapi tidak bermakna secara statistik (P = 0,426 >0,05). Simpulan: IL-10 secara konsisten meningkat setelah COT dan sebagai biomarker COT yang lebih baik daripada leukosit perifer.Kata kunci: IL-10, leukosit, COT

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JURNAL BIOMEDIK (JBM)

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