{"title":"乳凝胶:促进药物局部吸收的研究进展","authors":"A. Shinde, A. Velhal, P. Jadhav, V. Redasani","doi":"10.52711/2231-5659.2022.00057","DOIUrl":null,"url":null,"abstract":"Emulgel is a developing topical drug delivery technique that, if more attempt is put for the preparations with majority of topically effective drugs, will be a benefit for dermal care and cosmetic products due to its dual release control system (gel and emulsion). The direct availability of the skin as a target organ for diagnosis and treatment is a distinguishing characteristic of dermatological pharmacology. Transparent gels have grown in popularity as a crucialclass of semisolid preparations in both cosmetics and pharmaceuticals. Despite the many benefits of gels, one major limitation is the delivery of water insoluble drugs because solubility acts as a barricade and a problem arises during drug release. As a result, an emulsion-based strategy is being employed to bypass this barrier, allowing even a hydrophobic medicinal component to benefit from the special features of gels. Emulgels are dosage forms made up of gels and emulsions that have been mixed. The major goal is to generate a jellified emulsion that will reduce systemic side effects and produce a more prominent effect with fewer drug doses. Thixotropic, greaseless, good Spreadability, easily removable, soothing, soluble in water, long shelf life, bio-friendly, translucent & appealing look are only a few of the benefits of emulgels for dermatological use. As a result, emulgels can be utilize as a good topical drug delivery mechanism than the currently existing traditional systems.","PeriodicalId":8531,"journal":{"name":"Asian Journal of Research in Pharmaceutical Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A Review on Emulgel: Improvement of Topical Absorption of Drug\",\"authors\":\"A. Shinde, A. Velhal, P. Jadhav, V. Redasani\",\"doi\":\"10.52711/2231-5659.2022.00057\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Emulgel is a developing topical drug delivery technique that, if more attempt is put for the preparations with majority of topically effective drugs, will be a benefit for dermal care and cosmetic products due to its dual release control system (gel and emulsion). The direct availability of the skin as a target organ for diagnosis and treatment is a distinguishing characteristic of dermatological pharmacology. Transparent gels have grown in popularity as a crucialclass of semisolid preparations in both cosmetics and pharmaceuticals. Despite the many benefits of gels, one major limitation is the delivery of water insoluble drugs because solubility acts as a barricade and a problem arises during drug release. As a result, an emulsion-based strategy is being employed to bypass this barrier, allowing even a hydrophobic medicinal component to benefit from the special features of gels. Emulgels are dosage forms made up of gels and emulsions that have been mixed. The major goal is to generate a jellified emulsion that will reduce systemic side effects and produce a more prominent effect with fewer drug doses. Thixotropic, greaseless, good Spreadability, easily removable, soothing, soluble in water, long shelf life, bio-friendly, translucent & appealing look are only a few of the benefits of emulgels for dermatological use. As a result, emulgels can be utilize as a good topical drug delivery mechanism than the currently existing traditional systems.\",\"PeriodicalId\":8531,\"journal\":{\"name\":\"Asian Journal of Research in Pharmaceutical Sciences\",\"volume\":\"18 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Research in Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52711/2231-5659.2022.00057\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Research in Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/2231-5659.2022.00057","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Review on Emulgel: Improvement of Topical Absorption of Drug
Emulgel is a developing topical drug delivery technique that, if more attempt is put for the preparations with majority of topically effective drugs, will be a benefit for dermal care and cosmetic products due to its dual release control system (gel and emulsion). The direct availability of the skin as a target organ for diagnosis and treatment is a distinguishing characteristic of dermatological pharmacology. Transparent gels have grown in popularity as a crucialclass of semisolid preparations in both cosmetics and pharmaceuticals. Despite the many benefits of gels, one major limitation is the delivery of water insoluble drugs because solubility acts as a barricade and a problem arises during drug release. As a result, an emulsion-based strategy is being employed to bypass this barrier, allowing even a hydrophobic medicinal component to benefit from the special features of gels. Emulgels are dosage forms made up of gels and emulsions that have been mixed. The major goal is to generate a jellified emulsion that will reduce systemic side effects and produce a more prominent effect with fewer drug doses. Thixotropic, greaseless, good Spreadability, easily removable, soothing, soluble in water, long shelf life, bio-friendly, translucent & appealing look are only a few of the benefits of emulgels for dermatological use. As a result, emulgels can be utilize as a good topical drug delivery mechanism than the currently existing traditional systems.