E. Ricart, A. López-García, R. Barastegui, M. Gallego
{"title":"骨髓移植用于治疗难治性克罗恩病","authors":"E. Ricart, A. López-García, R. Barastegui, M. Gallego","doi":"10.1016/j.eii.2016.09.007","DOIUrl":null,"url":null,"abstract":"<div><p>Crohn's disease affects a part of the young population and has a strong impact on quality of life. Its etiology is unknown and existing drugs are not curative. In addition, a significant proportion of patients present intolerance, refractoriness, or loss of response to available medical therapies, and surgery is not a good option due to the extent or location of the disease. In recent years, a thorough investigation into new ways of dealing with refractory Crohn's disease is being developed, with new medical therapeutic targets but also cell therapy, including stem cell transplant, with encouraging results.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"16 2","pages":"Pages 70-76"},"PeriodicalIF":0.0000,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.09.007","citationCount":"0","resultStr":"{\"title\":\"Trasplante de médula ósea para el tratamiento de la enfermedad de Crohn refractaria\",\"authors\":\"E. Ricart, A. López-García, R. Barastegui, M. Gallego\",\"doi\":\"10.1016/j.eii.2016.09.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Crohn's disease affects a part of the young population and has a strong impact on quality of life. Its etiology is unknown and existing drugs are not curative. In addition, a significant proportion of patients present intolerance, refractoriness, or loss of response to available medical therapies, and surgery is not a good option due to the extent or location of the disease. In recent years, a thorough investigation into new ways of dealing with refractory Crohn's disease is being developed, with new medical therapeutic targets but also cell therapy, including stem cell transplant, with encouraging results.</p></div>\",\"PeriodicalId\":100473,\"journal\":{\"name\":\"Enfermedad Inflamatoria Intestinal al Día\",\"volume\":\"16 2\",\"pages\":\"Pages 70-76\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.eii.2016.09.007\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Enfermedad Inflamatoria Intestinal al Día\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1696780116300951\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Enfermedad Inflamatoria Intestinal al Día","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1696780116300951","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Trasplante de médula ósea para el tratamiento de la enfermedad de Crohn refractaria
Crohn's disease affects a part of the young population and has a strong impact on quality of life. Its etiology is unknown and existing drugs are not curative. In addition, a significant proportion of patients present intolerance, refractoriness, or loss of response to available medical therapies, and surgery is not a good option due to the extent or location of the disease. In recent years, a thorough investigation into new ways of dealing with refractory Crohn's disease is being developed, with new medical therapeutic targets but also cell therapy, including stem cell transplant, with encouraging results.