饮食和生活方式改变在阿曼冠状动脉血管重建术患者斑块复发生物标志物二级预防中的作用

Q3 Pharmacology, Toxicology and Pharmaceutics
Amanat Ali, Noura S.M. Al-Alawi, M. Sadiq, M. Waly
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引用次数: 1

摘要

目的:评估各种饮食和生活方式的改变在阿曼冠状动脉血管重建术患者斑块复发生物标志物的二级预防中的作用。方法:在获得知情同意后,将苏丹卡布斯大学医院心脏病门诊的72例患者纳入研究。在一项基于问卷的研究中,我们收集了四种生活方式改变的数据;在个人访谈中,身体活动,体重减轻,饮食摄入和健康饮食模式以及吸烟或不吸烟状况。一份修改过的研究问卷,包括半定量食物频率问卷,用于评估研究参与者的人口统计信息、饮食模式、饮食质量指数得分和每日饮食摄入量。患者的基线特征、血运重建信息和生化实验室检测数据均来自医院电子记录系统。使用R-studio v.7和Microsoft excel v.7对数据进行统计分析。结果:男性受教育程度高于女性,活跃度高于女性。数据显示,16%的男性和女性患有糖尿病,10%的男性和21%的女性患有高血压,30%的男性和42%的女性患有糖尿病和高血压。48%的男性和63%的女性体重指数(BMI) >30。然而,在BMI、糖尿病和高血压状况方面,男女差异无统计学意义(P < 0.05)。男性和女性的营养知识都很差。尽管男性和女性的LDL-C和HDL-C值不同,但它们都在正常的治疗范围内。HbA1c、c反应蛋白均高于正常值,男女差异无统计学意义(P < 0.05)。男性的平均每日能量摄入(2694千卡)明显高于女性(1603千卡)。大量营养素对能量的比例贡献在可接受的大量营养素分布范围内。男性(75.5)和女性(74.6)的阿曼饮食评分无显著差异(P < 0.05),表明他们坚持健康的饮食模式。结论:研究结果表明,饮食和生活方式的改变在阿曼冠状动脉血管重建术患者斑块复发生物标志物的二级预防中起着重要作用。因此,建议通过行为咨询促进饮食和生活方式因素的健康改变,作为斑块复发风险的二级预防。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Dietary and Lifestyle Modifications in the Secondary Prevention of Biomarkers of Plaque recurrence in Omani Coronary Revascularized Patients -
Objective: To assess the role of various dietary and lifestyle modifications in the secondary prevention of biomarkers of plaque recurrence in Omani coronary revascularized patients.Methods: Seventy-two patients, from the outpatient cardiology clinic of Sultan Qaboos University Hospital, were included in the study after obtaining an informed consent. In a questionnaire-based study, we collected data about four lifestyle modifications; physical activity, weight reduction, dietary intake and healthy eating patterns and smoking or non-smoking status, in personal interviews. A modified previously validated study questionnaire, which comprised of a semi-quantitative food frequency questionnaire, was used to assess the demographic information, eating patterns, diet quality index score, and daily dietary intake of study participants. The data about patient’s baseline characteristics, revascularization information and biochemical laboratory tests was harvested from the SQUH’s electronic record system. The statistical analysis of data was made using R-studio v.7 and Microsoft excel v.7.Results: The males had higher educational level as compared to females and were more active than females. The data indicated that 16% males and females were diabetic, 10% males and 21% females were hypertensive, and 30% males and 42% females had both diabetes and hypertension. Forty eight percent males and 63% females had body mass index (BMI) >30. However, no significant (P < 0.05) differences were observed in the BMI, diabetes and hypertension status in males and females. Both genders had poor nutritional knowledge. Although the LDL-C and HDL-C values in males and females differed, they were within the normal therapeutic limits. The HbA1c and C-reactive protein values were above the normal ranges with no significant (P < 0.05) difference in both males and females. The average daily energy intake in males (2694 kcalories) was significantly higher compared to females (1603 kcalories). The proportionate contribution of energy from macronutrients was within the acceptable macronutrient distribution ranges. Omani diet score for males (75.5) and females (74.6) didn’t differ significantly (P < 0.05), indicating their adherence to healthy dietary patterns.Conclusions: The results suggest that dietary and lifestyle modifications play significant role in the secondary prevention of biomarkers of plaque recurrence in Omani coronary revascularized patients. Behavioral counseling to promote healthy modifications in dietary and lifestyle factors are therefore recommended in the secondary prevention of risk of plaque recurrence.
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Journal of Pharmacy and Nutrition Sciences
Journal of Pharmacy and Nutrition Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
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