骨髓细胞在疟疾免疫中的作用综述

C. Uchechukwu, Chinedu Eleonu Priscella, Iwuala Egondu, O. Florence
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引用次数: 4

摘要

疟疾仍然是热带世界发病率和死亡率的一个主要原因。对其复杂免疫学的研究多集中于宿主对疟原虫的适应性免疫。涉及骨髓细胞的先天免疫机制的作用尚未得到足够的重视。这篇综述强调了骨髓细胞在疟疾免疫中的关键作用,通过诸如寄生虫感知和消除、促炎活性和其他免疫成分的激活等机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Role of Myeloid Cells in Immunity to Malaria: A Review
Malaria has continued to be a major cause of morbidity and mortality in the Tropical World. Research on its complex immunology has focused more on the host adaptive immunity to the plasmodium parasite. The role of innate immune mechanisms involving myeloid cells has not been given adequate attention. This review highlights the key role of myeloid cells in immunity to malaria through such mechanisms as parasite sensing and elimination, pro inflammatory activities and activation of other immune components.
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