多囊卵巢综合征女性与体外受精和卵浆内单精子注射候选对照组的卵母细胞和胚胎质量比较

IF 0.8 Q4 REPRODUCTIVE BIOLOGY
Maliheh Afiat, N. Khadem, Elnaz Nayeri, Roya Jalali, S. Akhlaghi, Elaheh Akhgari, A. Attaranzadeh, F. Borzoee, Azadeh Khazaie, Behnaz Souizi
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引用次数: 4

摘要

目的:多囊卵巢综合征(PCOS)是女性不孕症最常见的原因。本研究的目的是比较PCOS女性与对照组体外受精/胞浆内单精子注射(IVF/ICSI)候选人的卵母细胞和胚胎质量。材料与方法:本研究由Milad不孕不育研究中心设计,采用前瞻性队列形式,对100例确诊为PCOS的不孕妇女(病例组)和男性因素(对照组)作为第一个IVF周期候选者进行研究。两组均在标准拮抗剂方案下进行卵巢刺激周期和ICSI。然后使用SPSS 16版软件对收集的数据进行处理和分析。结果:研究病例的平均年龄为35±3岁,卵母细胞坏死是两组患者的潜在病理因素(PCOS组和对照组分别为28%和26%)。此外,大多数胚胎属于1级或2级或8细胞胚胎。此外,移植胚胎数量最多的患者与8细胞和1级有关。PCOS组和对照组生化妊娠发生率分别高达31.91%和22%,导致两组的分娩率分别为72.73%和60%。最后,两组在胚胎、卵母细胞、移植胚胎、胚泡卵母细胞的质量和数量、受孕率方面均无显著差异(P < 0.05)。结论:根据本研究结果,PCOS患者与其他需要ICSI的患者在卵母细胞质量、胚胎和妊娠率方面均无差异。因此,此类病例同样可以从ICSI方法中获益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Oocyte and Embryo Quality in Women With Polycystic Ovary Syndrome and the Control Group Candidate for In Vitro Fertilization and Intracytoplasmic Sperm Injection
Objectives: Polycystic ovary syndrome (PCOS) is the most common cause of female infertility. The aim of this study was to compare the oocyte and embryo quality between the PCOS women with the control group candidate for in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI). Materials and Methods: The present study was designed at the Infertility Research Center of Milad in the prospective cohort format and was carried out on 100 cases of infertile women with confirmed PCOS (case group) and the male factor (control group) as the first IVF cycle candidates. Both groups underwent the ovary stimulation cycle and ICSI under the standard antagonist protocol. The collected data were then processed and analyzed using the SPSS software, version 16. Results: The average age of study cases was 35±3, and oocyte necrosis was the underlying pathological factor in both groups (28% and 26% in the PCOS and control groups, respectively). In addition, most embryones belonged to either grade 1 or 2 or were 8-cell embryos. Furthermore, the highest number of transferred embryos among the patients was related to the 8-cell and grade 1. The occurrences of biochemical pregnancy in the PCOS and control groups were up to 31.91% and 22%, respectively, leading to 72.73% and 60% childbirth in cases of both groups. Finally, there were no significant differences observed with respect to the quality and the quantity of the embryones, the oocyte, the transferred embryo, the germinal vesicle oocytes, and the rate of pregnancy among the two groups (P>0.05). Conclusions: According to the results of the present study, no differences were found concerning the oocyte quality, embryo, and the pregnancy rate between PCOS cases and any other patients requiring ICSI. Therefore, such cases can similarly benefit from ICSI methods as well.
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来源期刊
CiteScore
1.60
自引率
14.30%
发文量
8
期刊介绍: All kind of knowledge contributing to the development of science by its content, value, level and originality will be covered by IJWHR. Problems of public health and their solutions are at the head of the windows opening us to the world. The "International Journal of Women''s Health and Reproduction Sciences” is a modern forum for scientific communication, covering all aspects women health and reproduction sciences, in basic and clinical sciences, mainly including: -Medical Education in Women Health and Reproduction Sciences -Cardiology in Women Health-Related Reproductive Problems -Sports Medicine in Women Health and Reproduction Sciences -Psychiatry in Women Health-Related Reproductive Problems -Antioxidant Therapy in Reproduction Medicine Sciences -Nutrition in Women Health and Reproduction Sciences -Defense Androgen and Estrogen -Fertility and Infertility -Urogynecology -Endometriosis -Endocrinology -Breast Cancer -Menopause -Puberty -Eroticism -Pregnancy -Preterm Birth -Vaginal Diseases -Sex-Based Biology -Surgical Procedures -Nursing in Pregnancy -Obstetrics/Gynecology -Polycystic Ovary Syndrome -Hyperandrogenism in Females -Menstrual Syndrome and Complications -Oncology of Female Reproductive Organs -Traditional Medicine in Women Reproductive Health -Ultrasound in Women Health Reproduction sciences -Stem Cell Research In Women Reproduction Sciences -Complementary Medicine in Women Reproductive Health -Female Sexual Dysfunction: Pathophysiology & Treatment
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