{"title":"低糖高膳食纤维面条对自发性糖尿病Torii脂肪大鼠血糖水平的影响","authors":"K. Suruga, Tsuyoshi Tomita, K. Kadokura","doi":"10.35248/2155-9600.20.10.777","DOIUrl":null,"url":null,"abstract":"Background: Low-carbohydrate diets have been a popular nutrition therapy since the American Diabetes Association’s 2013 recommendation. Low-carbohydrate diets are effective at lowering blood glucose and hemoglobin A1c levels. Here, we suggested the new diets intake restriction methods using low-sugar, high-dietary fiber noodles for those consuming noodles regularly. This study aimed to investigate the effect of a 28 day low-sugar, high-dietary fiber noodles diet, containing okara and konjac, on blood glucose levels of Spontaneously Diabetic Torii fatty rats, a model for obese type 2 diabetes. Methods: Male, 7-week-old rats were divided into two groups. Group I was fed the AIN-93G as standard diet (n=6) as control group, and group II was fed the standard diet in which 50% dried low-sugar, high-dietary fiber noodles replaced cornstarch (n=6). Body weight, food intake, and blood glucose levels were measured once a week, and hemoglobin A1c and glycated albumin levels analyzed after 28 days administration. Following the 28 days, the rats were fasted, glucose (2,000 mg/kg body weight) was administrated for the oral glucose tolerance test. Results: The blood glucose, hemoglobin A1c, and glycated albumin levels of the low-sugar, high-dietary fiber noodles group were significantly lower than those of the control group, in which body weight gain was observed. Conclusion: This is the first report on the effectiveness of low-sugar, high-dietary fiber noodles on blood glucose levels in model rats. The low-sugar, high-dietary fiber noodles might be beneficial for diabetes or celiac disease patients who consume noodles.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"104 1","pages":"1-7"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Effect of Low-Sugar and High-Dietary Fiber Noodles Diet on Blood Glucose Levels in Spontaneously Diabetic Torii Fatty Rats\",\"authors\":\"K. Suruga, Tsuyoshi Tomita, K. Kadokura\",\"doi\":\"10.35248/2155-9600.20.10.777\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Low-carbohydrate diets have been a popular nutrition therapy since the American Diabetes Association’s 2013 recommendation. Low-carbohydrate diets are effective at lowering blood glucose and hemoglobin A1c levels. Here, we suggested the new diets intake restriction methods using low-sugar, high-dietary fiber noodles for those consuming noodles regularly. This study aimed to investigate the effect of a 28 day low-sugar, high-dietary fiber noodles diet, containing okara and konjac, on blood glucose levels of Spontaneously Diabetic Torii fatty rats, a model for obese type 2 diabetes. Methods: Male, 7-week-old rats were divided into two groups. Group I was fed the AIN-93G as standard diet (n=6) as control group, and group II was fed the standard diet in which 50% dried low-sugar, high-dietary fiber noodles replaced cornstarch (n=6). Body weight, food intake, and blood glucose levels were measured once a week, and hemoglobin A1c and glycated albumin levels analyzed after 28 days administration. Following the 28 days, the rats were fasted, glucose (2,000 mg/kg body weight) was administrated for the oral glucose tolerance test. Results: The blood glucose, hemoglobin A1c, and glycated albumin levels of the low-sugar, high-dietary fiber noodles group were significantly lower than those of the control group, in which body weight gain was observed. Conclusion: This is the first report on the effectiveness of low-sugar, high-dietary fiber noodles on blood glucose levels in model rats. The low-sugar, high-dietary fiber noodles might be beneficial for diabetes or celiac disease patients who consume noodles.\",\"PeriodicalId\":16764,\"journal\":{\"name\":\"Journal of Nutrition and Food Sciences\",\"volume\":\"104 1\",\"pages\":\"1-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nutrition and Food Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35248/2155-9600.20.10.777\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nutrition and Food Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2155-9600.20.10.777","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of Low-Sugar and High-Dietary Fiber Noodles Diet on Blood Glucose Levels in Spontaneously Diabetic Torii Fatty Rats
Background: Low-carbohydrate diets have been a popular nutrition therapy since the American Diabetes Association’s 2013 recommendation. Low-carbohydrate diets are effective at lowering blood glucose and hemoglobin A1c levels. Here, we suggested the new diets intake restriction methods using low-sugar, high-dietary fiber noodles for those consuming noodles regularly. This study aimed to investigate the effect of a 28 day low-sugar, high-dietary fiber noodles diet, containing okara and konjac, on blood glucose levels of Spontaneously Diabetic Torii fatty rats, a model for obese type 2 diabetes. Methods: Male, 7-week-old rats were divided into two groups. Group I was fed the AIN-93G as standard diet (n=6) as control group, and group II was fed the standard diet in which 50% dried low-sugar, high-dietary fiber noodles replaced cornstarch (n=6). Body weight, food intake, and blood glucose levels were measured once a week, and hemoglobin A1c and glycated albumin levels analyzed after 28 days administration. Following the 28 days, the rats were fasted, glucose (2,000 mg/kg body weight) was administrated for the oral glucose tolerance test. Results: The blood glucose, hemoglobin A1c, and glycated albumin levels of the low-sugar, high-dietary fiber noodles group were significantly lower than those of the control group, in which body weight gain was observed. Conclusion: This is the first report on the effectiveness of low-sugar, high-dietary fiber noodles on blood glucose levels in model rats. The low-sugar, high-dietary fiber noodles might be beneficial for diabetes or celiac disease patients who consume noodles.