抗NMDA受体脑炎合并畸胎瘤导致的双侧听力损失:病例报告

Ibrain Pub Date : 2023-06-25 DOI:10.1002/ibra.12116
Guo-Fang Zhang, Tao Liang, Yi-Kun Lv, Zhong Luo, Jun Zhang
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引用次数: 0

摘要

自身免疫性脑炎(AE)是中枢神经系统的一种自身免疫性疾病。临床表现包括认知功能障碍、精神行为异常、癫痫、运动障碍、语言障碍和记忆障碍。有些患者在就诊时并没有特征性的临床表现,因此很容易被误诊。自身免疫抗体来源于遗传和后天因素。临床资料发现,卵巢畸胎瘤与自身免疫性脑炎之间存在相关性。本病例报告了一名 34 岁的女性,2021 年被诊断为畸胎瘤相关的抗 N-甲基-D-天冬氨酸受体介导的自身免疫性脑炎,称为抗 N-甲基-D-天冬氨酸受体脑炎,并伴有双侧听力损失。通过本病例报告,希望临床医生关注自身免疫性脑炎,提高对自身免疫性脑炎特殊临床表现的认识,注重早期识别。这意味着临床医生应熟悉该病的代表性临床表现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Bilateral hearing loss caused by anti-NMDA receptor encephalitis with teratoma: A case report

Bilateral hearing loss caused by anti-NMDA receptor encephalitis with teratoma: A case report

Autoimmune encephalitis (AE) is an autoimmune disease in the central nervous system. Clinical manifestations include cognitive dysfunction, psychiatric-behavioral abnormalities, epilepsy, motor disorders, speech disorders, and memory impairment. Some patients do not have the characteristic clinical manifestations of the disease when they see a doctor, so they are easily diagnosed incorrectly. Autoimmune antibodies originate from genetic and acquired factors. Clinical data have found a correlation between ovarian teratoma and autoimmune encephalitis. This case reports a 34-year-old woman who was diagnosed with teratoma-associated anti-N-methyl-D- aspartate receptor-mediated autoimmune encephalitis called anti-N-methyl-D-aspartate receptor encephalitis with bilateral hearing loss in 2021. Through this case report, clinicians will pay attention to autoimmune encephalitis and raise awareness of the specific clinical manifestations of autoimmune encephalitis, and focus on early identification. It means that clinicians should be familiar with the representative clinical manifestations of the disease.

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