Long-Term Use of Non-Steroidal Anti-Inflammatory Drugs in Patients with Axial Spondyloarthritis to Suppress Acute Bone Marrow Inflammation in the Sacroiliac Joints

Long-term use of nonsteroidal anti-inflammatory drugs in daily therapeutic practice is not welcome and often causes rejection due to the potential for the development of a variety of adverse events. However, in axial spondyloarthritis, these drugs play the role of not only symptomatic therapy, but also modify the course of the disease. Therefore, they should be prescribed for a long period, much longer than that described in the instructions for the drug. A brief description of clinical cases of the use of various non-steroidal anti-inflammatory drugs lasting 3 or more months is presented. Against the background of good clinical efficacy, adverse events did not develop during many months of continuous use