达那唑的微生物转化

M. Choudhary, Azizuddin, Atta-ur-rahman
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引用次数: 22

摘要

Danazol(17 -羟基-17- pregna-2,4-dien-20-yno-[2,3- d]异恶唑)(1)与lini镰镰菌、黑曲霉和aphidicola头孢菌发酵产生17-羟基-2-(羟甲基)-17- -pregna- 4-en-20-yn-3-one(2)和17-羟基-2-(羟甲基)-17- pregna-1,4-dien-20-yn-3-one(3),而与cerus芽孢杆菌发酵1只产生化合物2。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microbial Transformation of Danazol
Danazol (17 -hydroxy-17 -pregna-2,4-dien-20-yno-[2,3- d ] isoxazole) ( 1 ) on fermentation with Fusarium lini , Aspergillus niger , and Cephalosporium aphidicola yielded 17 -hydroxy-2-(hydroxymethyl)-17- -pregn-4-en-20-yn-3-one ( 2 ) and 17 -hydroxy-2-(hydroxymethyl)-17 -pregna-1,4-dien-20-yn-3-one ( 3 ), while the fermentation of 1 with Bacillus cerus yielded compound 2 only.
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