洞察药物薄膜作为有吸引力的剂型

Noor Hameed Alsaide, Nidhal Khazaal Maraie
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引用次数: 0

摘要

市场上不同的传统剂型有许多缺点,包括患者不方便、在几个地点的应用有限、生物利用度可变以及专利到期。这些缺点促使制药公司寻找其他药物平台。负载有效成分的薄膜制备成柔性聚合物层,在制药工业中得到认可。它们易于制备,适合通过不同途径给药(克服若干障碍),包括眼、真皮、透皮、阴道、口服和其他途径。此外,薄膜不含有害化学物质,具有良好的药物稳定性。这篇综述的重点是药物薄膜作为替代剂型,需要进一步关注,以最大限度地发挥其性能和应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Insights into medicated films as attractive dosage forms
Different traditional dosage forms available in the market with many drawbacks including patient inconvenience, limited applications to several sites, variable bioavailability in addition to patent expiration. These drawbacks make pharmaceutical companies look for other drug platforms. Thin films loaded with active ingredients which are prepared as flexible polymer layer gaining acceptability in drug industry. They are easily prepared, adapted for administration of drug via different routes (to overcome several barriers) including ocular, dermal, transdermal, vaginal, oral and others. In additions, thin films are free of harmful chemicals and offer good drug stability. This review spotlights on the medicated thin films as alternative dosage forms that require further attention to maximize their performance and application.
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