甲状腺切除术新鲜标本细针抽吸薄膜的细胞形态学评价

Yılmaz Baş, H. Havva, E. Keser, H. Behice, E. Erenler
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引用次数: 0

摘要

目的:本研究旨在比较新甲状腺切除标本的细胞形态学与宏显微观察结果。研究设计:我们的研究共纳入75例甲状腺手术标本。病理学家对标本进行细针穿刺活检(FNAB)。将抽吸液放入TP液中,进行PAP染色。我们定义了细胞学检查结果,与宏观显微镜检查结果相一致。结果:细胞学检查良性结节108例,恶性结节18例,囊性结节2例。细胞学诊断与组织学上的良性结节110例,恶性结节18例相符。核沟/不规则核膜、核重叠/拥挤、核增大、核假包涵、苍白/细染色质是恶性病例中具有统计学意义的细胞学参数。结论:病理医师对活检各阶段的FNAB、组织形态学和TP PAP细胞学切片进行了评价。很明显,用这种方法从良性或恶性甲状腺结节中获得足够的细胞是多么重要。尽管细胞病理学家对t
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Cytomorphologic Evaluation of the Thin Prep for Fine Needle Aspirationof the Fresh Thyroidectomy Specimens
Objective: This study aimed to compare cytomorphology of ThinPrep Papanicolaou (TP PAP) method with the macroscopic-microscopic findings of the nodules on fresh thyroidectomy specimens. Study Design: A total of 75 thyroid surgical specimens were included in our study. Fine Needle Aspiration Biopsy (FNAB) of specimens was performed by a pathologist. Aspirate was taken into TP liquid and stained with PAP. We defined cytological findings, compatible with macroscopic-microscopic findings. Results: In cytologic evaluation 108 nodules were diagnosed benign, while 18 nodules were malignant and 2 cystic nodules were insufficient. Cytological diagnosis was compatible with histologically benign a total of 110 nodules, and 18 malignant nodules. Nuclear groove/irregular nuclear membrane, nuclear overlap/crowding, nuclear enlargement, nuclear pseudoinclusion, pale/fine chromatin are determined as statistically significant cytological parameters in malignant cases. Conclusion: FNAB and the histo-morphological and TP PAP cytological slides were evaluated by pathologists at every stage of biopsy process. It is clearly understood how important it is to obtain adequate cells from the benign or malignant thyroid nodules with this method. Although controversial opinions among the cytopathologists regarding t
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