HIV患者心理健康与抗逆转录病毒药物依从性的关系

Q4 Medicine
M. Heydari, Morteza Mehraeen, P. Keshani, M. Faghih
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引用次数: 1

摘要

背景:多种因素,如精神障碍,可能影响HIV/AIDS患者对药物的渴望和依从性。目的:本研究旨在确定艾滋病毒/艾滋病患者的神经障碍水平及其与高效抗逆转录病毒治疗(HAART)药物依从性的关系。材料与方法:采用简易法抽取设拉子市行为疾病咨询中心的150例患者,采用症状自评-25 (SCL-25)和药物依从性问卷(MAQ)进行评估。采用χ 2检验、Kruskal-Wallis检验、Mann-Whitney U检验,采用SPSS-20进行Spearman相关系数和logistic回归分析(P < 0.05)。结果:78%的患者心理健康状况正常。而且,83%的人有很好的药物依从性。女性、单身或离婚、从事临时工作和低收入工作与心理健康状况下降有关。年龄和教育程度越高,依从性越高。焦虑是最常见和最有效的障碍。精神健康状况下降会降低药物依从性。结论:治疗精神障碍,特别是焦虑症,是提高艾滋病患者药物依从性的最有效方法之一。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Association Between Mental Health of HIV Patients and Antiretroviral Medication Adherence
Background: Various factors, like mental disorders, may affect the desire for medication and adherence in HIV/AIDS patients. Objectives: The present study aimed to determine levels of neurotic disorders and associations of disorders level and Highly Active Antiretroviral Therapy (HAART) medication adherence in HIV/AIDS patients. Materials and Methods: Finally, 150 patients of Behavioral Disease Counseling Center of Shiraz were selected by a convenience method and were evaluated by Symptom Checklist-25 (SCL-25) and Medication Adherence Questionnaire (MAQ). Chi-square, Kruskal-Wallis, Mann-Whitney U tests were, Spearman's correlation coefficient and logistic regression were used to analyze the data by using SPSS-20 (P < 0.05). Results: Seventy-eight percent of patients had normal mental health status. Also, 83% had very good medication adherence. Female gender, single or divorced, and working in temporary and low-income jobs were associated with decreased mental health status. Higher age and education were associated with increased adherence. Anxiety was the most common and effective disorder. Decreased mental health' status was shown to reduce drug adherence. Conclusions: Treatment of mental disorders, particularly anxiety, can be one of the most effective ways to increase drug compliance in HIV/AIDS patients.
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
18
期刊介绍: International Journal of High Risk Behaviors and Addiction is a clinical journal which is informative to all fields related to the high risk behaviors, addiction, including smoking, alcohol consumption and substance abuse, unsafe sexual behavior, obesity and unhealthy eating habits, physical inactivity, and violence, suicidal behavior, and self-injurious behaviors. International Journal of High Risk Behaviors and Addiction is an authentic clinical journal which its content is devoted to the particular compilation of the latest worldwide and interdisciplinary approach and findings including original manuscripts, meta-analyses and reviews, health economic papers, debates, and consensus statements of the clinical relevance of Risky behaviors and addiction. In addition, consensus evidential reports not only highlight the new observations, original research and results accompanied by innovative treatments and all the other relevant topics but also include highlighting disease mechanisms or important clinical observations and letters on articles published in this journal.
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