{"title":"辣椒2(E)， 4(E)-十二烯酸对酵母脂质积累的抑制作用","authors":"J. Irie, Y. Morita, M. Murata, S. Homma","doi":"10.3136/FSTI9596T9798.3.409","DOIUrl":null,"url":null,"abstract":"Inhibitors of lipid accumulation in Lipomyces starkeyi were screened from various kinds of foods from the point of anti-obesity. An extract of black pepper showed inhibition of lipid accumulation with apparently weak repression of its growth. An active component was isolated from black pepper and was identified as 2(E),4(E)-decadienoic acid by instrumental analyses. Pepper contains about 20 mg/100 g of 2(E),4(E)-decadienoic acid. The minimum inhibitory concentrations of 2(E),4(E)-decadienoic acid against microbial growth ranged from 60 to 1000 μg/ml. The acid inhibited the growth of L. starkeyi at 100 μg/ml and the lipid accumulation at 12-50 μg/ml. The repression of lipid accumulation in L. starkeyi by 2(E),4(E)-decadienoic acid seemed to be due to the inhibition of glycerol-3-phosphate dehydrogenase and growth.","PeriodicalId":12457,"journal":{"name":"Food Science and Technology International, Tokyo","volume":"216 1","pages":"409-413"},"PeriodicalIF":0.0000,"publicationDate":"1997-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Inhibition of Lipid Accumulation in Lipomyces Yeast by 2(E), 4(E)-Decadienoic Acid from Pepper.\",\"authors\":\"J. Irie, Y. Morita, M. Murata, S. Homma\",\"doi\":\"10.3136/FSTI9596T9798.3.409\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Inhibitors of lipid accumulation in Lipomyces starkeyi were screened from various kinds of foods from the point of anti-obesity. An extract of black pepper showed inhibition of lipid accumulation with apparently weak repression of its growth. An active component was isolated from black pepper and was identified as 2(E),4(E)-decadienoic acid by instrumental analyses. Pepper contains about 20 mg/100 g of 2(E),4(E)-decadienoic acid. The minimum inhibitory concentrations of 2(E),4(E)-decadienoic acid against microbial growth ranged from 60 to 1000 μg/ml. The acid inhibited the growth of L. starkeyi at 100 μg/ml and the lipid accumulation at 12-50 μg/ml. The repression of lipid accumulation in L. starkeyi by 2(E),4(E)-decadienoic acid seemed to be due to the inhibition of glycerol-3-phosphate dehydrogenase and growth.\",\"PeriodicalId\":12457,\"journal\":{\"name\":\"Food Science and Technology International, Tokyo\",\"volume\":\"216 1\",\"pages\":\"409-413\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1997-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Science and Technology International, Tokyo\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3136/FSTI9596T9798.3.409\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Science and Technology International, Tokyo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3136/FSTI9596T9798.3.409","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Inhibition of Lipid Accumulation in Lipomyces Yeast by 2(E), 4(E)-Decadienoic Acid from Pepper.
Inhibitors of lipid accumulation in Lipomyces starkeyi were screened from various kinds of foods from the point of anti-obesity. An extract of black pepper showed inhibition of lipid accumulation with apparently weak repression of its growth. An active component was isolated from black pepper and was identified as 2(E),4(E)-decadienoic acid by instrumental analyses. Pepper contains about 20 mg/100 g of 2(E),4(E)-decadienoic acid. The minimum inhibitory concentrations of 2(E),4(E)-decadienoic acid against microbial growth ranged from 60 to 1000 μg/ml. The acid inhibited the growth of L. starkeyi at 100 μg/ml and the lipid accumulation at 12-50 μg/ml. The repression of lipid accumulation in L. starkeyi by 2(E),4(E)-decadienoic acid seemed to be due to the inhibition of glycerol-3-phosphate dehydrogenase and growth.
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