Diah Dwi Lestari, A. R. Affandi, E. Retnowati, Iffah Muflihati
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引用次数: 0

摘要

COVID-19大流行仍然是一个严重的问题。保持身体的免疫力需要意识。姜黄是一种抗氧化剂含量高的根茎,具有提高人体免疫力的潜力。姜黄是一种常用的草药形式,可将其转化为泡腾片中的制剂,具有更大的实用优势。本研究旨在探讨姜黄提取物和维生素C添加浓度对抗氧化值、物理特性和感官的影响。试验设计采用两因子析因设计,即姜黄提取物浓度(30%和40%)和维生素C浓度(5%、10%和15%)。研究阶段包括提取液和泡腾片的制备。结果表明,C15K40样品的IC50值最高,为0.88。片剂重量均匀性符合印尼药典标准。各处理泡腾片的溶出时间差异显著,最快值为190秒,颜色试验结果表明,姜黄提取物的加入对泡腾片的颜色有影响。感官测试显示没有显著差异,但总体上C10K30样本更受小组成员的青睐。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FORMULASI PEMBUATAN TABLET EFFERVESCENT MENGGUNAKAN EKSTRAK KUNYIT DENGAN PENAMBAHAN VITAMIN C
COVID-19 pandemic is still serious problem. Awareness is needed to maintain body' immunity. Turmeric is a type of rhizome that high antioxidant content that has potential to increase body immunity. Turmeric is commonly consumed form of herbal medicine, which can be converted into preparations in the effervescent tablets with more practical advantages. This study aims to examine the effect of adding concentration of turmeric extract and vitamin C to the antioxidant value, physical characteristics, and organoleptic. The experimental design used a factorial design with two factors, namely concentration of turmeric extract (30% and 40%) and concentration of vitamin C (5, 10, and 15%). The research stages include process of making extracts and then making effervescent tablets. The results showed that the antioxidant activity was expressed highest IC50 in the C15K40 sample with a value of 0.88. The uniformity of tablet weight has complied with Indonesian pharmacopoeial standards. The dissolution time of effervescent tablets of all treatments was significantly different with the fastest value of 190 seconds, the color test results showed that color was influenced by addition of turmeric extract. Organoleptic testing showed no significant difference, but overall the C10K30 sample was preferred by panelists.
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