细菌phbv -导管用于神经再生对大鼠氧化应激参数的影响

M. Demirbilek, M. Demirbilek, E. Erdal, M. Sakar, G. Bozkurt
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引用次数: 1

摘要

在手术后第17周,使用纳米纤维在腹膜PHBV导管中形成1cm间隙形成的导管。测定导管周围及血清的丙二醛(MDA)、氧化蛋白产物(AOPP)、谷胱甘肽和超氧化物歧化酶。与对照组相比,各移植组血清MDA、AOPP、GSH水平及SOD活性均显著升高,组织中只有MDA、AOPP水平有统计学意义升高。因此,这些发现提示PHBV神经移植用于大鼠坐骨神经缺损可能导致氧化应激。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of bacterial PHBV-conduit used for nerve regeneration on oxidative stress parameters in rats
in or its on antioxidant by electrospinning and conduits formed by using the nanofiber the of a 1 cm gap in the peritoneal PHBV conduits sacri 17th week after the operations. (MDA), oxidation protein products (AOPP), glutathione and superoxide dismutase of as as surrounding of conduits and serums were measured. Compared to control groups, MDA, AOPP and GSH levels and SOD activites in all graft group serums showed a significant increase, while only MDA and AOPP levels in tissues were statistically higher. Therefore, these findings suggest that PHBV nerve graft used for sciatic nerve defects may lead to oxidative stress in rats.
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