骨组织工程用可生物降解聚磷腈-羟基磷灰石复合材料

IF 2.5 4区医学 Q4 MATERIALS SCIENCE, BIOMATERIALS

International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2023-09-22 DOI:10.1080/00914037.2022.2082426

A. Subash, Abina Basanth, B. Kandasubramanian

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引用次数: 5

摘要

骨组织工程(bone tissue engineering, BTE)在过去的几年里受到了人们的广泛关注，因为它能够精确地控制细胞和细胞外基质(extracellular matrix, ECM)的时空分布，从而消除了传统骨移植中存在的健康问题。由于其特殊的性能，聚合物作为BTE生物材料的突出类别之一受到了极大的关注。聚磷腈/羟基磷灰石复合材料的相容性、生物相容性、生物活性和生物降解性使其成为功能性骨再生的候选材料。本文综述了聚磷腈、羟基磷灰石及BTE复合生物材料的合成、性能及应用。图形抽象

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Biodegradable polyphosphazene – hydroxyapatite composites for bone tissue engineering

Abstract The venture to fabricate potential and functional bone regeneration, annihilating the health complexities in conventional bone grafting, made Bone tissue engineering (BTE), which facilitates meticulous control of the spatial and temporal dissemination of cells and extracellular matrix (ECM), receive incredible consideration in the past few years. Ascribable to their exceptional properties, polymers have gotten significant attention as one of the prominent classes of biomaterials for BTE. The compatible mechanical properties, biocompatibility, bioactivity, and biodegradability of polyphosphazene/hydroxyapatite composite made them candidates for functional bone regeneration. This review demonstrates the synthesis, properties, and application of polyphosphazenes, hydroxyapatite, and composite biomaterial for BTE. Graphical Abstract

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来源期刊

International Journal of Polymeric Materials and Polymeric Biomaterials Chemical Engineering-General Chemical Engineering

CiteScore

8.00

自引率

3.10%

发文量

审稿时长

3.3 months

期刊介绍： International Journal of Polymeric Materials and Polymeric Biomaterials is the official publication of the International Society for Biomedical Polymers and Polymeric Biomaterials (ISBPPB). This journal provides a forum for the publication of peer-reviewed, English language articles and select reviews on all aspects of polymeric materials and biomedical polymers. Being interdisciplinary in nature, this journal publishes extensive contributions in the areas of encapsulation and controlled release technologies to address innovation needs as well.