Christopher R. Smith, Lars D. Engstrom, S. Kulyk, Ruth Aranda, Laurie Waters, K. Moya, Vickie Bowcut, Allan Hebbert, David Trinh, David M Briere, J. Lawson, Jeff Clarine, L. Rahbaek, J. Christensen, M. Marx, P. Olson
{"title":"P165: MRTX1719:一种mta协同PRMT5抑制剂,在MTAP/CDKN2A缺失的癌症模型中选择性地激发抗肿瘤活性","authors":"Christopher R. Smith, Lars D. Engstrom, S. Kulyk, Ruth Aranda, Laurie Waters, K. Moya, Vickie Bowcut, Allan Hebbert, David Trinh, David M Briere, J. Lawson, Jeff Clarine, L. Rahbaek, J. Christensen, M. Marx, P. Olson","doi":"10.1158/1535-7163.targ-21-p165","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Abstract P165: MRTX1719: A first-in-class MTA-cooperative PRMT5 inhibitor that selectively elicits antitumor activity in MTAP/CDKN2A deleted cancer models\",\"authors\":\"Christopher R. Smith, Lars D. Engstrom, S. Kulyk, Ruth Aranda, Laurie Waters, K. Moya, Vickie Bowcut, Allan Hebbert, David Trinh, David M Briere, J. Lawson, Jeff Clarine, L. Rahbaek, J. Christensen, M. Marx, P. Olson\",\"doi\":\"10.1158/1535-7163.targ-21-p165\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":20348,\"journal\":{\"name\":\"Poster Presentations - Proffered Abstracts\",\"volume\":\"6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Poster Presentations - Proffered Abstracts\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1158/1535-7163.targ-21-p165\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Poster Presentations - Proffered Abstracts","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1158/1535-7163.targ-21-p165","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Abstract P165: MRTX1719: A first-in-class MTA-cooperative PRMT5 inhibitor that selectively elicits antitumor activity in MTAP/CDKN2A deleted cancer models