合成无机纳米材料白羽衣虫对埃及伊蚊的体内毒性评价

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Main Group Chemistry Pub Date : 2022-02-21 DOI:10.3233/mgc-220003

Ahmed N. Al-hakimi, S. K. Alhag, M. Abdulghani, L. Aroua, J. Mahyoub

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引用次数: 1

摘要

利用白鸡蛋花叶提取物制备银纳米粒子(AgNPs)和金纳米粒子(AuNPs)防治埃及伊蚊。采用紫外可见光谱、傅里叶变换红外辐射(FTIR)、x射线衍射(XRD)和透射电子显微镜(TEM)对合成的AgNPs和AuNPs进行了表征。对伊蚊的敏感程度。测定埃及伊蚊幼虫对植物提取物白桦叶提取物及其银纳米粒子(AgNPs)和金纳米粒子的免疫活性。AgNPs和AuNPs光谱分别在300 nm和500 nm处显示出最大吸收。AgNPs和AuNPs的致死率分别为69.9592 ppm和88.2635 ppm，而白叶青叶水提液的LC50为178.4713 ppm。此外，白杨提取物的纳米颗粒制剂10000 ppm剂量长达一周没有显著影响，在给药后7天内既没有出现中毒迹象，也没有死亡。然而，当大鼠再观察7天时，没有明显的延迟毒性迹象。目前的研究表明，白叶提取物、AgNPs和AuNPs对动物具有生物安全性，对埃及伊蚊具有生态友好性。

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Evaluation of synthesized inorganic nanomaterials Plumeria alba against Aedes aegypti and in vivo toxicity

Silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) were fabricated using Plumeria alba leaf extracts to control the mosquito Aedes aegypti. Synthesized AgNPs and AuNPs were characterized by ultraviolet-visible spectroscopy, Fourier-Transform Infrared Radiation (FTIR) spectroscopy, X-ray diffraction (XRD), and transmission electron microscope (TEM) analysis. Susceptibility levels of Ae. aegypti mosquito larvae to the plant extract P.alba and its silver nanoparticles (AgNPs) and gold nanoparticles were determined. The AgNPs and AuNPs spectra displayed their maximum absorption at 300 nm and 500 nm, respectively. The larval mortality of AgNPs and AuNPs were highly effective LC50 were 69.9592 ppm and 88.2635 ppm compared to the aqueous leaf extract of P. alba LC50 was 178.4713 ppm. Furthermore, no significant effects of nanoparticle preparations of P. alba extract 10,000 ppm dose up to one week revealed neither toxic signs nor death within seven days of administration. However, there were no apparent signs of delayed toxicity when the rats were observed for an additional seven days. Current studies revealed that the P. alba leaf extract, AgNPs and AuNPs are biologically safe on animals and eco-friendly for control of Aedes aegypti mosquito.

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来源期刊

Main Group Chemistry 化学-化学综合

CiteScore

2.00

自引率

26.70%

发文量

审稿时长

>12 weeks

期刊介绍： Main Group Chemistry is intended to be a primary resource for all chemistry, engineering, biological, and materials researchers in both academia and in industry with an interest in the elements from the groups 1, 2, 12–18, lanthanides and actinides. The journal is committed to maintaining a high standard for its publications. This will be ensured by a rigorous peer-review process with most articles being reviewed by at least one editorial board member. Additionally, all manuscripts will be proofread and corrected by a dedicated copy editor located at the University of Kentucky.