Fernanda Nascimento de Oliveira , Cristina Eunice Okuyama , Audrey de Souza Marquez , Karen Barros Parron Fernandes , Paulo Victor Carpaneze Dalaqua , Andréia Cristina Feitosa do Carmo , Fátima Cristina Alves Branco-Barreiro
{"title":"巴哈花疗法在儿童和青少年注意缺陷多动障碍中的应用:系统回顾和荟萃分析","authors":"Fernanda Nascimento de Oliveira , Cristina Eunice Okuyama , Audrey de Souza Marquez , Karen Barros Parron Fernandes , Paulo Victor Carpaneze Dalaqua , Andréia Cristina Feitosa do Carmo , Fátima Cristina Alves Branco-Barreiro","doi":"10.1016/j.aimed.2023.07.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div><span>To systematically review the available evidence of the effect of Bach flower remedies (BFR) on the improvement of symptoms and behavior in children and adolescents </span>with attention deficit hyperactivity disorder (ADHD).</div></div><div><h3>Methods</h3><div>This systematic review<span> with meta-analysis was developed following PRISMA recommendations and the protocol was registered in PROSPERO. The search for controlled trials was performed in Cochrane Central Register of Controlled Trials<span>, Embase, PubMed and LILACS and in grey literature from their inceptions until March, 2023. The population was children and adolescents diagnosed with ADHD. The intervention included the use BFR and the control included placebo or conventional therapies group. The outcome included improvement of symptoms and behavior. RoB 2.0 was used to assess the risk of bias, while GRADE was used to assess the quality of evidence. Stata version 16.0 was used to perform the meta-analysis.</span></span></div></div><div><h3>Results</h3><div><span>Of the 457 studies identified, only 4 studies that met the inclusion criteria remained and were included in the data analysis. The agreement between the reviewers for risk of bias assessment, based on the kappa statistic, was 0.91. Three studies reported improvement in ADHD symptoms with BFR. The studies presented some concerns regarding the risk of bias and the quality of evidence was “low”. The meta-analysis showed a positive effect favoring BFR (z = 2.57, p = 0.01) </span><em>versus</em><span> control with an effect size of 0.80 (0.19–1.42:95 %CI). I</span><sup>2</sup> test value was 35.96 %, indicating moderate heterogeneity among the studies.</div></div><div><h3>Conclusions</h3><div>BFR can have some effect on ADHD. However, further studies with higher methodological quality and long-term follow-up period are needed to reinforce these findings.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"10 3","pages":"Pages 93-100"},"PeriodicalIF":1.7000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Use of Bach flower remedies in children and adolescents with attention deficit hyperactivity disorder: Systematic review and meta-analysis\",\"authors\":\"Fernanda Nascimento de Oliveira , Cristina Eunice Okuyama , Audrey de Souza Marquez , Karen Barros Parron Fernandes , Paulo Victor Carpaneze Dalaqua , Andréia Cristina Feitosa do Carmo , Fátima Cristina Alves Branco-Barreiro\",\"doi\":\"10.1016/j.aimed.2023.07.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div><span>To systematically review the available evidence of the effect of Bach flower remedies (BFR) on the improvement of symptoms and behavior in children and adolescents </span>with attention deficit hyperactivity disorder (ADHD).</div></div><div><h3>Methods</h3><div>This systematic review<span> with meta-analysis was developed following PRISMA recommendations and the protocol was registered in PROSPERO. The search for controlled trials was performed in Cochrane Central Register of Controlled Trials<span>, Embase, PubMed and LILACS and in grey literature from their inceptions until March, 2023. The population was children and adolescents diagnosed with ADHD. The intervention included the use BFR and the control included placebo or conventional therapies group. The outcome included improvement of symptoms and behavior. RoB 2.0 was used to assess the risk of bias, while GRADE was used to assess the quality of evidence. Stata version 16.0 was used to perform the meta-analysis.</span></span></div></div><div><h3>Results</h3><div><span>Of the 457 studies identified, only 4 studies that met the inclusion criteria remained and were included in the data analysis. The agreement between the reviewers for risk of bias assessment, based on the kappa statistic, was 0.91. Three studies reported improvement in ADHD symptoms with BFR. The studies presented some concerns regarding the risk of bias and the quality of evidence was “low”. The meta-analysis showed a positive effect favoring BFR (z = 2.57, p = 0.01) </span><em>versus</em><span> control with an effect size of 0.80 (0.19–1.42:95 %CI). I</span><sup>2</sup> test value was 35.96 %, indicating moderate heterogeneity among the studies.</div></div><div><h3>Conclusions</h3><div>BFR can have some effect on ADHD. However, further studies with higher methodological quality and long-term follow-up period are needed to reinforce these findings.</div></div>\",\"PeriodicalId\":7343,\"journal\":{\"name\":\"Advances in integrative medicine\",\"volume\":\"10 3\",\"pages\":\"Pages 93-100\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in integrative medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212958823000745\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in integrative medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212958823000745","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Use of Bach flower remedies in children and adolescents with attention deficit hyperactivity disorder: Systematic review and meta-analysis
Objective
To systematically review the available evidence of the effect of Bach flower remedies (BFR) on the improvement of symptoms and behavior in children and adolescents with attention deficit hyperactivity disorder (ADHD).
Methods
This systematic review with meta-analysis was developed following PRISMA recommendations and the protocol was registered in PROSPERO. The search for controlled trials was performed in Cochrane Central Register of Controlled Trials, Embase, PubMed and LILACS and in grey literature from their inceptions until March, 2023. The population was children and adolescents diagnosed with ADHD. The intervention included the use BFR and the control included placebo or conventional therapies group. The outcome included improvement of symptoms and behavior. RoB 2.0 was used to assess the risk of bias, while GRADE was used to assess the quality of evidence. Stata version 16.0 was used to perform the meta-analysis.
Results
Of the 457 studies identified, only 4 studies that met the inclusion criteria remained and were included in the data analysis. The agreement between the reviewers for risk of bias assessment, based on the kappa statistic, was 0.91. Three studies reported improvement in ADHD symptoms with BFR. The studies presented some concerns regarding the risk of bias and the quality of evidence was “low”. The meta-analysis showed a positive effect favoring BFR (z = 2.57, p = 0.01) versus control with an effect size of 0.80 (0.19–1.42:95 %CI). I2 test value was 35.96 %, indicating moderate heterogeneity among the studies.
Conclusions
BFR can have some effect on ADHD. However, further studies with higher methodological quality and long-term follow-up period are needed to reinforce these findings.
期刊介绍:
Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.