{"title":"性腺外型生殖细胞松果体肿瘤1例","authors":"M. Chilimoniuk, E. Olszewska, A. Kiluk","doi":"10.5114/WO.2011.26443","DOIUrl":null,"url":null,"abstract":"The pineal region is the most common area for germ cell tumours. They are mostly observed in children. In adults they are more common in men in the second or third decade of life. Pineal tu mours have a diverse histopathology. Their growth is slow and the symptoms result from the compression of adjacent cerebral structures. One of the histopathological forms is germinal tumours, including mild or malignant teratoma. They have the ability to release neoplastic markers, e.g. AFP, β-HCG, which are used to evaluate the effectiveness of surgical and oncological treatment. The paper presents a case of a 24-year-old man di agnosed as teratocarcinoma. The treat ment protocol consisted of both surgery and conventional fractionation radio therapy (Df = 1.8 Gy, 5 ◊ weekly) to the total dose of 50.4 Gy. After a few months, there was a recurrence of the cancer process. The patient received 2 courses of chemotherapy, which did not yield the expected therapeutic effect. The patient’s prognosis is unfavourable due to rapid local relapse and failure after treatment. The case is presented due to the rarity of pineal teratocarcinoma tu mours and the age of the patient.","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":"47 1","pages":"399-403"},"PeriodicalIF":2.9000,"publicationDate":"2011-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extragonadal form of germ cell pineal tumour: a case report\",\"authors\":\"M. Chilimoniuk, E. Olszewska, A. Kiluk\",\"doi\":\"10.5114/WO.2011.26443\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The pineal region is the most common area for germ cell tumours. They are mostly observed in children. In adults they are more common in men in the second or third decade of life. Pineal tu mours have a diverse histopathology. Their growth is slow and the symptoms result from the compression of adjacent cerebral structures. One of the histopathological forms is germinal tumours, including mild or malignant teratoma. They have the ability to release neoplastic markers, e.g. AFP, β-HCG, which are used to evaluate the effectiveness of surgical and oncological treatment. The paper presents a case of a 24-year-old man di agnosed as teratocarcinoma. The treat ment protocol consisted of both surgery and conventional fractionation radio therapy (Df = 1.8 Gy, 5 ◊ weekly) to the total dose of 50.4 Gy. After a few months, there was a recurrence of the cancer process. The patient received 2 courses of chemotherapy, which did not yield the expected therapeutic effect. The patient’s prognosis is unfavourable due to rapid local relapse and failure after treatment. The case is presented due to the rarity of pineal teratocarcinoma tu mours and the age of the patient.\",\"PeriodicalId\":49354,\"journal\":{\"name\":\"Wspolczesna Onkologia-Contemporary Oncology\",\"volume\":\"47 1\",\"pages\":\"399-403\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2011-12-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Wspolczesna Onkologia-Contemporary Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/WO.2011.26443\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wspolczesna Onkologia-Contemporary Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/WO.2011.26443","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Extragonadal form of germ cell pineal tumour: a case report
The pineal region is the most common area for germ cell tumours. They are mostly observed in children. In adults they are more common in men in the second or third decade of life. Pineal tu mours have a diverse histopathology. Their growth is slow and the symptoms result from the compression of adjacent cerebral structures. One of the histopathological forms is germinal tumours, including mild or malignant teratoma. They have the ability to release neoplastic markers, e.g. AFP, β-HCG, which are used to evaluate the effectiveness of surgical and oncological treatment. The paper presents a case of a 24-year-old man di agnosed as teratocarcinoma. The treat ment protocol consisted of both surgery and conventional fractionation radio therapy (Df = 1.8 Gy, 5 ◊ weekly) to the total dose of 50.4 Gy. After a few months, there was a recurrence of the cancer process. The patient received 2 courses of chemotherapy, which did not yield the expected therapeutic effect. The patient’s prognosis is unfavourable due to rapid local relapse and failure after treatment. The case is presented due to the rarity of pineal teratocarcinoma tu mours and the age of the patient.
期刊介绍:
Contemporary Oncology is a journal aimed at oncologists, oncological surgeons, hematologists, radiologists, pathologists, radiotherapists, palliative care specialists, psychologists, nutritionists, and representatives of any other professions, whose interests are related to cancer. Manuscripts devoted to basic research in the field of oncology are also welcomed.