性腺外型生殖细胞松果体肿瘤1例

IF 2.9 Q2 ONCOLOGY
M. Chilimoniuk, E. Olszewska, A. Kiluk
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引用次数: 0

摘要

松果体区域是生殖细胞肿瘤最常见的区域。它们主要发生在儿童身上。在成年人中,他们在生命的第二或第三个十年中更常见。松果体瘤具有多种组织病理学。它们生长缓慢,症状是由于邻近的大脑结构受到压迫。其中一种组织病理学形式是生发性肿瘤,包括轻度或恶性畸胎瘤。它们具有释放肿瘤标志物的能力,例如AFP, β-HCG,这些标志物用于评估手术和肿瘤治疗的有效性。本文提出了一个24岁的男子诊断为畸胎癌的情况。治疗方案包括手术和常规分割放射治疗(Df = 1.8 Gy,每周5次),总剂量为50.4 Gy。几个月后,癌症又复发了。患者接受了2个疗程的化疗,未达到预期的治疗效果。由于局部快速复发和治疗失败,患者预后不利。这个病例是由于罕见的松果体畸胎瘤和病人的年龄提出的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Extragonadal form of germ cell pineal tumour: a case report
The pineal region is the most common area for germ cell tumours. They are mostly observed in children. In adults they are more common in men in the second or third decade of life. Pineal tu mours have a diverse histopathology. Their growth is slow and the symptoms result from the compression of adjacent cerebral structures. One of the histopathological forms is germinal tumours, including mild or malignant teratoma. They have the ability to release neoplastic markers, e.g. AFP, β-HCG, which are used to evaluate the effectiveness of surgical and oncological treatment. The paper presents a case of a 24-year-old man di agnosed as teratocarcinoma. The treat ment protocol consisted of both surgery and conventional fractionation radio therapy (Df = 1.8 Gy, 5 ◊ weekly) to the total dose of 50.4 Gy. After a few months, there was a recurrence of the cancer process. The patient received 2 courses of chemotherapy, which did not yield the expected therapeutic effect. The patient’s prognosis is unfavourable due to rapid local relapse and failure after treatment. The case is presented due to the rarity of pineal teratocarcinoma tu mours and the age of the patient.
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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
22
审稿时长
4-8 weeks
期刊介绍: Contemporary Oncology is a journal aimed at oncologists, oncological surgeons, hematologists, radiologists, pathologists, radiotherapists, palliative care specialists, psychologists, nutritionists, and representatives of any other professions, whose interests are related to cancer. Manuscripts devoted to basic research in the field of oncology are also welcomed.
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