哈里亚纳邦南部一家三级保健医院中艾滋病毒血清阳性和艾滋病毒血清阴性病例中乙型和丙型肝炎合并感染的血清患病率

Shreya Behl, Aaditya Behl, Prof. Vanita Mane, Jyoti Sangwan, P. Vohra
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摘要

HBV(乙型肝炎病毒)和HCV(丙型肝炎病毒)是急性和慢性肝炎的病原体。全世界有近20亿人感染乙型肝炎病毒,约1.7亿人感染丙型肝炎病毒。在感染艾滋病毒(人类免疫缺陷病毒)的患者中,发现有200万至400万人同时感染慢性乙型肝炎病毒,有400万至500万人同时感染丙型肝炎病毒。由于HIV、HBV和HCV的常见传播方式,如共用针头、注射器、其他注射器具、性交,甚至母婴传播,在HIV阳性个体中,HBV和HCV合并感染是很常见的。这是一项基于医院的观察性横断面研究。这项研究是在哈里亚纳邦努赫纳尔哈尔SHKM GMC微生物学系进行的。那是一年。HIV血清阳性病例的样本量为80例,其中HIV阳性和HIV阴性各40例。在HIV阳性和HIV阴性样本中检测到HBV和HCV的血清阳性率。HBV和HCV的血清阳性率在HIV阳性人群中高于HIV阴性人群。HIV阳性患者中HBsAg阳性10%,HBeAg阳性5%,HBV RT-PCR阳性10%。所有HIV阴性患者均未合并HBV感染。同样,在快速检测、ELISA和RT-PCR中,12.5%的个体中发现HCV-HIV合并感染。没有HIV阴性的人同时感染HCV。HIV阳性人群中HBV和HCV合并感染,HIV阴性人群中未见HBV和HCV合并感染。建议对HIV阳性个体进行HBV和HCV的定期筛查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seroprevalence of Hepatitis B and C co-infection in HIV seropositive and HIV seronegative cases in a Tertiary care hospital in Southern Haryana
HBV (Hepatitis B virus) and HCV (Hepatitis C virus) are the causative agents of acute as well as chronic hepatitis. Nearly, two billion people are suffering with HBV and approximately 170 million people are infected with HCV infection around the world. While patients who are infected with HIV (Human Immunodeficiency Virus) 2-4 million are found to be having chronic HBV co-infection and 4-5 million are having HCV coinfection. Due to common mode of transmission of HIV, HBV and HCV like using shared needles, syringes, other injectable devices, sexual intercourse, or even mother to baby transmission, it is common to see HBV and HCV co-infection in HIV positive individuals. This was a hospital based observational cross-sectional study. This study was conducted in Department of Microbiology, SHKM GMC, Nalhar, Nuh, Haryana. It was for one year. The sample size for HIV seropostive cases was 80 including 40 HIV positive and 40 HIV negative samples. Seroprevalence of HBV and HCV was identified on HIV positive and HIV negative samples. Seroprevalence of HBV and HCV was found to be higher in HIV positive individuals than HIV negative individuals. In HIV positive patients 10% individuals were HBsAg positive, 5% were HBeAg positive, 10% were positive by HBV RT-PCR. None of the HIV negative were coinfected with HBV. Similarly HCV-HIV coinfection was seen in 12.5% of individuals with Rapid test, ELISA and RT-PCR. None of the HIV negative were coinfected with HCV. In HIV positive individuals HBV and HCV coinfection was seen and Co-infection of HBV and HCV was absent in HIV negative individuals. Regular screening is recommended for HBV and HCV in HIV positive individuals.
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