超短激光对视网膜的损伤机制及安全性

IF 2.9 2区医学 Q2 BIOCHEMICAL RESEARCH METHODS

Biomedical optics express Pub Date : 1999-06-14 DOI:10.1117/12.349987

B. Rockwell, C. Toth, W. Roach, D. J. Payne, R. Hopkins, P. Kennedy, D. Stolarski, G. Noojin, R. Thomas, C. Cain

{"title":"超短激光对视网膜的损伤机制及安全性","authors":"B. Rockwell, C. Toth, W. Roach, D. J. Payne, R. Hopkins, P. Kennedy, D. Stolarski, G. Noojin, R. Thomas, C. Cain","doi":"10.1117/12.349987","DOIUrl":null,"url":null,"abstract":"For the past several years the US Air Force has led a research effort to investigate the thresholds and mechanisms for retinal damage from ultrashort laser pulses [i.e. nanosecond (10-9 sec) to femtosecond (10-15 sec) pulse widths]. The goal was to expand the biological database into the ultrashort pulse regime and thus to allow establishment of maximum permissible exposure limits for these lasers. We review the progress made in determining trends in retial damage by ultrashort laser pulses in the visible and near infrared, including variations in spot size and number of pulses. We also discuss the most likely damage mechanisms operative in this pulse width regime and discuss relevance to laser safety.","PeriodicalId":8969,"journal":{"name":"Biomedical optics express","volume":"46 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"1999-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Retinal damage mechanisms and safety for ultrashort laser exposure\",\"authors\":\"B. Rockwell, C. Toth, W. Roach, D. J. Payne, R. Hopkins, P. Kennedy, D. Stolarski, G. Noojin, R. Thomas, C. Cain\",\"doi\":\"10.1117/12.349987\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"For the past several years the US Air Force has led a research effort to investigate the thresholds and mechanisms for retinal damage from ultrashort laser pulses [i.e. nanosecond (10-9 sec) to femtosecond (10-15 sec) pulse widths]. The goal was to expand the biological database into the ultrashort pulse regime and thus to allow establishment of maximum permissible exposure limits for these lasers. We review the progress made in determining trends in retial damage by ultrashort laser pulses in the visible and near infrared, including variations in spot size and number of pulses. We also discuss the most likely damage mechanisms operative in this pulse width regime and discuss relevance to laser safety.\",\"PeriodicalId\":8969,\"journal\":{\"name\":\"Biomedical optics express\",\"volume\":\"46 1\",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"1999-06-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical optics express\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1117/12.349987\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical optics express","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1117/12.349987","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}

引用次数: 3

摘要

在过去的几年里，美国空军一直致力于研究超短激光脉冲(即纳秒(10-9秒)到飞秒(10-15秒)脉冲宽度)对视网膜损伤的阈值和机制。目标是将生物数据库扩展到超短脉冲范围，从而允许建立这些激光器的最大允许照射限制。我们回顾了超短激光脉冲在可见光和近红外波段对视网膜损伤趋势的研究进展，包括光斑大小和脉冲数的变化。我们还讨论了在这个脉冲宽度范围内最可能的损伤机制，并讨论了与激光安全的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Retinal damage mechanisms and safety for ultrashort laser exposure

For the past several years the US Air Force has led a research effort to investigate the thresholds and mechanisms for retinal damage from ultrashort laser pulses [i.e. nanosecond (10-9 sec) to femtosecond (10-15 sec) pulse widths]. The goal was to expand the biological database into the ultrashort pulse regime and thus to allow establishment of maximum permissible exposure limits for these lasers. We review the progress made in determining trends in retial damage by ultrashort laser pulses in the visible and near infrared, including variations in spot size and number of pulses. We also discuss the most likely damage mechanisms operative in this pulse width regime and discuss relevance to laser safety.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS

CiteScore

6.80

自引率

11.80%

发文量

633

审稿时长

1 months

期刊介绍： The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.