脂溢性皮炎:维生素治疗的独特可能性

N. Reznichenko, G. Reznichenko, S. A. Smiian, Y. Reznichenko
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引用次数: 0

摘要

在实际皮肤病学中,脂溢性皮炎问题被积极地认为是人群中最常见的病理状况。目的-研究使用自然素类药物治疗脂溢性皮炎患者的临床有效性和安全性。材料和方法。150例脂溢性皮炎患者被纳入研究。对照组包括50名同龄的健康人士。脂溢性皮炎的严重程度是通过评分量表来确定的,该评分量表包括对皮肤红斑、肿胀、湿润、擦伤、脱皮和脂肪的强度的评估。焦虑水平根据斯皮尔伯格-哈宁自尊量表评估,神经质水平根据沃瑟曼的诊断方法评估。一项调查也使用贝克量表对抑郁症的严重程度进行了自我评估。根据治疗方法,将脂溢性皮炎患者分为两组:I(实验)- 100例患者接受纳图生物素药物,剂量为5 mg,每天一次,持续3个月;II(对照组):50例接受标准治疗的患者。结果和讨论。在脂溢性皮炎的治疗方案中额外加入纳图生物素药物,确保100%的患者恢复,头皮和面部的病理过程定位。只有5.3%的脂溢性皮炎患者有轻微的鳞屑和脂肪性皮肤。纳入纳图生物素药物治疗后,I组患者的脂溢性皮炎严重程度积分评估指标均明显优于接受标准治疗的II组。使用纳妥比素后,瘙痒、睡眠障碍等主观症状的评估也明显改善。生物素维生素治疗有助于显著减少患者的焦虑、抑郁和神经质状态。所获得的数据表明,自然生物素治疗脂溢性皮炎具有很高的疗效。脂溢性皮炎的病程伴随着高度的个人和状态焦虑,神经质的增加和抑郁的倾向。使用纳妥比素治疗脂溢性皮炎是合理和适当的,因为它提供了一个快速和持久的临床效果,皮肤状况的正常化和改善患者的心理状态。所获得的结果给予理由,建议广泛使用自然生物素药物治疗脂溢性皮炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seborrheic dermatitis: unique possibilities of vitamin therapy
In practical dermatology, the problem of seborrheic dermatitis is actively considered as the most common pathological condition among the population Objective — to study the clinical effectiveness and safety of the use of the Natubiotin drug in the treatment of patients with seborrheic dermatitis. Materials and methods. 150 patients with seborrheic dermatitis were included in the study. The control group included 50 healthy people of the same age. The severity of seborrheic dermatitis was determined using a scoring scale that included evaluation of the intensity of erythema, swelling, wetting, excoriations, peeling, and fattiness of the skin. The level of anxiety was estimated according to the Spielberger—Khanin self-esteem scale, the level of neuroticism — according to the diagnostic method of L.I. Wasserman. A survey was also conducted using the Beck scale for self-assessment of the severity of depression. Depending on the method of treatment, patients with seborrheic dermatitis were divided into two groups: I (experimental) — 100 patients who received Natubiotin drug in a dose of 5 mg once a day for 3 months; II (control) — 50 patients who underwent standard therapy. Results and discussion. Additional inclusion of Natubiotin drug in the treatment regimen of seborrheic dermatitis ensured the recovery of 100 % patients with localization of the pathological process on the scalp and face. Only 5.3 % of patients with localization of seborrheic dermatitis on the trunk had slight scaling and fattiness of the skin. After the treatment with the inclusion of Natubiotin drug, the indicators of the point assessment of the severity of seborrheic dermatitis in patients of group I were significantly better than in group II that received standard therapy. The assessment of subjective symptoms such as itching and sleep disturbances were also significantly better after using Natubiotin. Vitamin therapy with biotin contributed to a significant reduction of state anxiety, depression and neuroticism in patients. The obtained data indicate the high effectiveness of Natubiotin for the treatment of seborrheic dermatitis. Conclusions. The course of seborrheic dermatitis is accompanied by high personal and state anxiety, increased neuroticism and tendency to depression. Therapy of seborrheic dermatitis with the use of Natubiotin is justified and appropriate, as it provides a quick and long­lasting clinical effect, normalization of the skin condition and improvement of the psychogenic state of patients. The obtained results give reason to recommend the widespread use of Natubiotin drug for the treatment of seborrheic dermatitis.
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