J. González-González, Oscar Zúñiga-Lemus, M. C. Hernández-Galindo
{"title":"机械化学制备茶碱和咖啡因的水合固体形式","authors":"J. González-González, Oscar Zúñiga-Lemus, M. C. Hernández-Galindo","doi":"10.9790/3013-0705012830","DOIUrl":null,"url":null,"abstract":"Caffeine and theophylline are methyl-xantine drugs, which are affected by water leading to their hydrated forms. The purpose of this work was to prepare and characterize hydrated forms of caffeine and theophylline by mechanochemistry. The obtained products were characterized by infrared spectroscopy and Xray powder diffraction. The infrared spectra and diffractograms of the ground products were similar to the reported for caffeine and theophylline hydrates.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"22 1","pages":"28-30"},"PeriodicalIF":0.0000,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"9","resultStr":"{\"title\":\"Hydrated Solid Forms of Theophylline and Caffeine Obtained by Mechanochemistry\",\"authors\":\"J. González-González, Oscar Zúñiga-Lemus, M. C. Hernández-Galindo\",\"doi\":\"10.9790/3013-0705012830\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Caffeine and theophylline are methyl-xantine drugs, which are affected by water leading to their hydrated forms. The purpose of this work was to prepare and characterize hydrated forms of caffeine and theophylline by mechanochemistry. The obtained products were characterized by infrared spectroscopy and Xray powder diffraction. The infrared spectra and diffractograms of the ground products were similar to the reported for caffeine and theophylline hydrates.\",\"PeriodicalId\":14540,\"journal\":{\"name\":\"IOSR Journal of Pharmacy\",\"volume\":\"22 1\",\"pages\":\"28-30\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IOSR Journal of Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9790/3013-0705012830\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/3013-0705012830","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hydrated Solid Forms of Theophylline and Caffeine Obtained by Mechanochemistry
Caffeine and theophylline are methyl-xantine drugs, which are affected by water leading to their hydrated forms. The purpose of this work was to prepare and characterize hydrated forms of caffeine and theophylline by mechanochemistry. The obtained products were characterized by infrared spectroscopy and Xray powder diffraction. The infrared spectra and diffractograms of the ground products were similar to the reported for caffeine and theophylline hydrates.
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