两波段原子超流体系统的两波段原子结果分析结果对超导材料的指导作用

Andrew J. Vincent, T. D. Silva
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引用次数: 0

摘要

了解鸟嘌呤四联体(G4s)在遗传水平上为广泛的疾病及其潜在治疗提供了有价值的见解。这些不寻常的结构可以在DNA和RNA中形成,由四个氢键鸟嘌呤的平面堆叠四分体组成。G4s广泛涉及一系列疾病类别,包括寄生虫、病毒感染、癌症和神经退行性疾病,并在每种疾病中发挥不同的作用。与当前相关的是,与冠状病毒家族的联系可能是调查最近疫情的一个有趣途径。G4四分体的平面也为小分子结合物提供了一个有吸引力的靶标,可以提供治疗价值。综上所述,本文旨在阐述G4s在这些领域的相关性,一些主要的作用机制,以及它们作为治疗靶点的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analytical Results for Two-Band Atomic Results for Two-Band Atomic Superfluid System as a Guidance for Superconducting Materials
Understanding Guanine Quadruplexes (G4s) provides valuable insight into a wide array of diseases at a genetic level and their potential therapy. These unusual architectures can form in DNA and RNA, composed of planar, stacked tetrads of four hydrogen bonded guanines. G4s are widely implicated in a range of disease categories, including parasites, viral infections, cancer, and neurodegenerative diseases, with varied roles within each. Of current relevance, a connection to the coronavirus family may be an intriguing avenue of investigation for recent outbreaks. The planar surface of the G4 tetrad also provides an attractive target for small molecule binders that can provide therapeutic value. Overall, this review aims to address the exciting relevance of G4s in these fields, a few major mechanisms of action, and their potential as therapeutic targets.
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