{"title":"注射曲安奈德、透明质酸酶联合富血小板血浆(PRP)治疗口腔黏膜下纤维化的比较研究。","authors":"Deepankar Chandrakapure, Kavita Sachdeva, Kajal Agarwal, Amrita Shukla","doi":"10.1007/s12070-023-03912-0","DOIUrl":null,"url":null,"abstract":"<p><p>This study aimed to compare the results of injection triamcinolone and hyaluronidase combination with injection Platelet Rich Plasma (PRP) in management of Oral Submucous Fibrosis (OSMF). Present study was carried out in randomly divided two groups of 30 patients each of OSMF who all are presented with chief complain of reduced mouth opening. Group A patients were given 1 ml of injection triamcinolone and hyaluronidase combination. Group B patients received 1 ml of injection Platelet Rich Plasma. Both injections were given intralesionally once a week for 6 weeks. Results of ANOVA shows significant better results in improving mouth opening in group B patients receiving injection Platelet Rich Plasma as a treatment. In Group A, patients shows improvement in Maximum interincisal distance (MIID) of mean 6.51 ± 1.02 mm as compared to the patients in group B shows improvement in MIID of mean 9.53 ± 1.06 mm (<i>p</i> value < 0.05). Treatment of OSMF with injection Platelet Rich Plasma is a novel method and found to be more efficient than treatment with injection triamcinolone and hyaluronidase combination.</p>","PeriodicalId":51825,"journal":{"name":"Ecosistemas","volume":"1 1","pages":"3725-3732"},"PeriodicalIF":0.8000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645765/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparative Study of Injection Triamcinolone and Hyaluronidase Combination with Injection Platelet Rich Plasma (PRP) in Management of Oral Submucous Fibrosis (OSMF).\",\"authors\":\"Deepankar Chandrakapure, Kavita Sachdeva, Kajal Agarwal, Amrita Shukla\",\"doi\":\"10.1007/s12070-023-03912-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study aimed to compare the results of injection triamcinolone and hyaluronidase combination with injection Platelet Rich Plasma (PRP) in management of Oral Submucous Fibrosis (OSMF). Present study was carried out in randomly divided two groups of 30 patients each of OSMF who all are presented with chief complain of reduced mouth opening. Group A patients were given 1 ml of injection triamcinolone and hyaluronidase combination. Group B patients received 1 ml of injection Platelet Rich Plasma. Both injections were given intralesionally once a week for 6 weeks. Results of ANOVA shows significant better results in improving mouth opening in group B patients receiving injection Platelet Rich Plasma as a treatment. In Group A, patients shows improvement in Maximum interincisal distance (MIID) of mean 6.51 ± 1.02 mm as compared to the patients in group B shows improvement in MIID of mean 9.53 ± 1.06 mm (<i>p</i> value < 0.05). Treatment of OSMF with injection Platelet Rich Plasma is a novel method and found to be more efficient than treatment with injection triamcinolone and hyaluronidase combination.</p>\",\"PeriodicalId\":51825,\"journal\":{\"name\":\"Ecosistemas\",\"volume\":\"1 1\",\"pages\":\"3725-3732\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645765/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ecosistemas\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s12070-023-03912-0\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/7/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"ECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ecosistemas","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12070-023-03912-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ECOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
本研究旨在比较注射曲安奈德和透明质酸酶联合注射富血小板血浆(PRP)治疗口腔黏膜下纤维化(OSMF)的结果。本研究随机分为两组,每组30例OSMF患者,均以开口缩小为主诉。A组患者给予曲安奈德与透明质酸酶联合注射1 ml。B组患者给予富血小板血浆1 ml注射。两种注射剂均每周一次局部注射,连续6周。方差分析结果显示,B组患者接受富血小板血浆注射治疗后,改善口腔张开的效果明显更好。A组患者最大内切距离(MIID)平均改善6.51±1.02 mm, B组患者最大内切距离(MIID)平均改善9.53±1.06 mm (p值
Comparative Study of Injection Triamcinolone and Hyaluronidase Combination with Injection Platelet Rich Plasma (PRP) in Management of Oral Submucous Fibrosis (OSMF).
This study aimed to compare the results of injection triamcinolone and hyaluronidase combination with injection Platelet Rich Plasma (PRP) in management of Oral Submucous Fibrosis (OSMF). Present study was carried out in randomly divided two groups of 30 patients each of OSMF who all are presented with chief complain of reduced mouth opening. Group A patients were given 1 ml of injection triamcinolone and hyaluronidase combination. Group B patients received 1 ml of injection Platelet Rich Plasma. Both injections were given intralesionally once a week for 6 weeks. Results of ANOVA shows significant better results in improving mouth opening in group B patients receiving injection Platelet Rich Plasma as a treatment. In Group A, patients shows improvement in Maximum interincisal distance (MIID) of mean 6.51 ± 1.02 mm as compared to the patients in group B shows improvement in MIID of mean 9.53 ± 1.06 mm (p value < 0.05). Treatment of OSMF with injection Platelet Rich Plasma is a novel method and found to be more efficient than treatment with injection triamcinolone and hyaluronidase combination.
期刊介绍:
ECOSISTEMAS es la revista científica de ecología y medio ambiente de la Asociación Española de Ecología Terrestre. Desde el año 2001 se publica exclusivamente en formato electrónico cada cuatro meses. La revista publica artículos científicos originales sobre ecología y medio ambiente incluyendo investigación sobre organismos, poblaciones, comunidades y ecosistemas, interacciones biológicas, paleoecología, ecofisiología, eco-evolución y procesos ecosistémicos, así como sobre perturbaciones antropogénicas y sus efectos a nivel ecológico y ambiental. Todas las contribuciones deben ser originales y no haber sido publicadas previamente en la literatura científica. Serán considerados para su publicación solamente trabajos de índole científica que presenten datos nuevos analizados de forma adecuada o trabajos novedosos de revisión bibliográfica que constituyan una aportación importante al tema. Los trabajos descriptivos sin una interpretación y discusión detallada del significado ecológico que puede extraerse de los resultados escritos, los que reflejen una opinión personal, o que sean puramente especulativos sin resultados claros que apoyen las conclusiones descritas, serán rechazados a nivel editorial. Todas las contribuciones son publicadas en castellano, con título, resumen y pies de figuras y tablas también en inglés. Nuestro objetivo es ser la revista científica de ecología y medio ambiente de referencia para los países y comunidades hispanohablantes. No se repercute tasa o coste alguno a los autores en concepto de gestión o publicación de sus propuestas.