A. Wu, A. Mair, I. Papieva, Ayda Taha, Neelam Dhingra
{"title":"第三次的魅力:加强全球努力,减少与药物有关的伤害","authors":"A. Wu, A. Mair, I. Papieva, Ayda Taha, Neelam Dhingra","doi":"10.1177/25160435221120362","DOIUrl":null,"url":null,"abstract":"I begin every day taking the same pill regimen: a cholesterol-lowering agent for familial hyperlipidemia, a proton-pump inhibitor for gastrointestinal reflux, and an over-the-counter antihistamine for chronic allergies. (AW) I am not exceptional. Over half of US adults take two or more pills a day, and nearly half take three prescription medications a week, putting me squarely in the middle of the road. Worldwide, numbers are slightly lower but comparable. For older adults the numbers are greater: three out of five older adults in the US take five or more prescriptions a day. Prescription medications help people around the world treat medical conditions, but they can also cause harm if overused, underused, not monitored, or otherwise misused. Since the beginning of the patient safety era, unsafe medication practices and medication errors have been the leading cause of injury and avoidable harm in health care systems across the globe. But most people, most of the time, fail to appreciate the potential downsides of medication use. The need to take multiple medications can be just as problematic, resulting in frequent health care contacts and an increased likelihood of medication related harm. These risks proliferate in specific situations, and at transition points at different levels, locations, and settings of care. Medication errors occur at every point in the labyrinthine medication use system. At the center lie prescribing, ordering, storage, dispensing, preparation, administration, and monitoring practices. Medication errors are multidimensional and may occur because of the weak medication systems and practices, which face increasing numbers of medications, routes of delivery and formulations, human factors, complexity of use, and broader system issues. In many cases, unsafe medication practices can result in severe harm, disability and even death. Although countless strategies have been developed to address the frequency and impact of medication errors, their implementation has been variable. We assert that patients and families can play a key role in taking medications safely and effectively. Healthcare professionals need to ensure that patients are empowered to do this. The COVID-19 pandemic highlighted many areas where medications were used inappropriately. Some were not supported by scientific studies, such as ivermectin and hydroxchloroquine, and caused significant harms. There were conspicuous examples of inappropriate antibiotic prescribing. Antibiotic use has been described in more than 70% of cases of COVID-19, often for the suspicion of bacterial superinfection in one series this was judged inappropriate in over a third. There were many cases related to the use of complementary and alternative medicines, used despite limited evidence for their effectiveness. Moreover, the disruptions in the health care systems caused by the pandemic resulted in more frequent self-care practices, which also has implications for medication safety. There were many other examples of inappropriate medication use, which is synonymous with increased risk of harm. For example, medications for non-communicable disease were not reviewed In particular, medications for anxiety and depression were used without review or monitoring. Recognizing the scale of avoidable harm linked with unsafe medication practices, the third WHO Global Patient Safety Challenge: Medication Without Harm was launched in Bonn, Germany in 2017. The Strategic Framework of the Challenge calls for a systemic approach to address medication safety, by acting across four key domains: patients and the public, health care professionals, medicines and systems and practices of medication. As part of the Challenge, WHO has asked key stakeholders worldwide to prioritize and take early action in three key areas associated with significant patient harm due to unsafe medication practices:","PeriodicalId":73888,"journal":{"name":"Journal of patient safety and risk management","volume":"10 1","pages":"157 - 159"},"PeriodicalIF":0.6000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Third Time’s the Charm: Strengthening Global Efforts to Reduce Medication-Related Harm\",\"authors\":\"A. Wu, A. Mair, I. Papieva, Ayda Taha, Neelam Dhingra\",\"doi\":\"10.1177/25160435221120362\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"I begin every day taking the same pill regimen: a cholesterol-lowering agent for familial hyperlipidemia, a proton-pump inhibitor for gastrointestinal reflux, and an over-the-counter antihistamine for chronic allergies. (AW) I am not exceptional. Over half of US adults take two or more pills a day, and nearly half take three prescription medications a week, putting me squarely in the middle of the road. Worldwide, numbers are slightly lower but comparable. For older adults the numbers are greater: three out of five older adults in the US take five or more prescriptions a day. Prescription medications help people around the world treat medical conditions, but they can also cause harm if overused, underused, not monitored, or otherwise misused. Since the beginning of the patient safety era, unsafe medication practices and medication errors have been the leading cause of injury and avoidable harm in health care systems across the globe. But most people, most of the time, fail to appreciate the potential downsides of medication use. The need to take multiple medications can be just as problematic, resulting in frequent health care contacts and an increased likelihood of medication related harm. These risks proliferate in specific situations, and at transition points at different levels, locations, and settings of care. Medication errors occur at every point in the labyrinthine medication use system. At the center lie prescribing, ordering, storage, dispensing, preparation, administration, and monitoring practices. Medication errors are multidimensional and may occur because of the weak medication systems and practices, which face increasing numbers of medications, routes of delivery and formulations, human factors, complexity of use, and broader system issues. In many cases, unsafe medication practices can result in severe harm, disability and even death. Although countless strategies have been developed to address the frequency and impact of medication errors, their implementation has been variable. We assert that patients and families can play a key role in taking medications safely and effectively. Healthcare professionals need to ensure that patients are empowered to do this. The COVID-19 pandemic highlighted many areas where medications were used inappropriately. Some were not supported by scientific studies, such as ivermectin and hydroxchloroquine, and caused significant harms. There were conspicuous examples of inappropriate antibiotic prescribing. Antibiotic use has been described in more than 70% of cases of COVID-19, often for the suspicion of bacterial superinfection in one series this was judged inappropriate in over a third. There were many cases related to the use of complementary and alternative medicines, used despite limited evidence for their effectiveness. Moreover, the disruptions in the health care systems caused by the pandemic resulted in more frequent self-care practices, which also has implications for medication safety. There were many other examples of inappropriate medication use, which is synonymous with increased risk of harm. For example, medications for non-communicable disease were not reviewed In particular, medications for anxiety and depression were used without review or monitoring. Recognizing the scale of avoidable harm linked with unsafe medication practices, the third WHO Global Patient Safety Challenge: Medication Without Harm was launched in Bonn, Germany in 2017. The Strategic Framework of the Challenge calls for a systemic approach to address medication safety, by acting across four key domains: patients and the public, health care professionals, medicines and systems and practices of medication. As part of the Challenge, WHO has asked key stakeholders worldwide to prioritize and take early action in three key areas associated with significant patient harm due to unsafe medication practices:\",\"PeriodicalId\":73888,\"journal\":{\"name\":\"Journal of patient safety and risk management\",\"volume\":\"10 1\",\"pages\":\"157 - 159\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of patient safety and risk management\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/25160435221120362\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of patient safety and risk management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/25160435221120362","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
Third Time’s the Charm: Strengthening Global Efforts to Reduce Medication-Related Harm
I begin every day taking the same pill regimen: a cholesterol-lowering agent for familial hyperlipidemia, a proton-pump inhibitor for gastrointestinal reflux, and an over-the-counter antihistamine for chronic allergies. (AW) I am not exceptional. Over half of US adults take two or more pills a day, and nearly half take three prescription medications a week, putting me squarely in the middle of the road. Worldwide, numbers are slightly lower but comparable. For older adults the numbers are greater: three out of five older adults in the US take five or more prescriptions a day. Prescription medications help people around the world treat medical conditions, but they can also cause harm if overused, underused, not monitored, or otherwise misused. Since the beginning of the patient safety era, unsafe medication practices and medication errors have been the leading cause of injury and avoidable harm in health care systems across the globe. But most people, most of the time, fail to appreciate the potential downsides of medication use. The need to take multiple medications can be just as problematic, resulting in frequent health care contacts and an increased likelihood of medication related harm. These risks proliferate in specific situations, and at transition points at different levels, locations, and settings of care. Medication errors occur at every point in the labyrinthine medication use system. At the center lie prescribing, ordering, storage, dispensing, preparation, administration, and monitoring practices. Medication errors are multidimensional and may occur because of the weak medication systems and practices, which face increasing numbers of medications, routes of delivery and formulations, human factors, complexity of use, and broader system issues. In many cases, unsafe medication practices can result in severe harm, disability and even death. Although countless strategies have been developed to address the frequency and impact of medication errors, their implementation has been variable. We assert that patients and families can play a key role in taking medications safely and effectively. Healthcare professionals need to ensure that patients are empowered to do this. The COVID-19 pandemic highlighted many areas where medications were used inappropriately. Some were not supported by scientific studies, such as ivermectin and hydroxchloroquine, and caused significant harms. There were conspicuous examples of inappropriate antibiotic prescribing. Antibiotic use has been described in more than 70% of cases of COVID-19, often for the suspicion of bacterial superinfection in one series this was judged inappropriate in over a third. There were many cases related to the use of complementary and alternative medicines, used despite limited evidence for their effectiveness. Moreover, the disruptions in the health care systems caused by the pandemic resulted in more frequent self-care practices, which also has implications for medication safety. There were many other examples of inappropriate medication use, which is synonymous with increased risk of harm. For example, medications for non-communicable disease were not reviewed In particular, medications for anxiety and depression were used without review or monitoring. Recognizing the scale of avoidable harm linked with unsafe medication practices, the third WHO Global Patient Safety Challenge: Medication Without Harm was launched in Bonn, Germany in 2017. The Strategic Framework of the Challenge calls for a systemic approach to address medication safety, by acting across four key domains: patients and the public, health care professionals, medicines and systems and practices of medication. As part of the Challenge, WHO has asked key stakeholders worldwide to prioritize and take early action in three key areas associated with significant patient harm due to unsafe medication practices: