回顾了不粘附性的测量方法,重点是化学粘附性测试

Hanad Osman , Randah Alghamdi , Pankaj Gupta
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引用次数: 4

摘要

相当数量的心血管疾病患者不按规定服药。这可能导致疾病并发症、住院和死亡的风险增加。因此,有必要确定准确检测患者不依从的方法,以确保患者可以被识别和参与。这将允许向这些患者提供足够的支持,以提高依从率,从而导致更好的疾病结局。这篇综述着眼于广泛的方法来建立药物不依从性。特别关注化学粘附性测试,因为这种方法已被许多高血压诊所所接受,并已被欧洲指南推荐用于疑似顽固性高血压患者。这篇综述讨论了目前在高血压诊所使用的化学依从性测试,也讨论了不依从性背后的一些原因,并提供了可以与患者讨论的解决方案,以克服这些挑战。临床医生和患者之间关于化学依从性测试结果的讨论需要在无指责的环境中进行,以确保患者能够与临床医生进行公开和诚实的讨论。临床医生和医疗保健专业人员需要更多的培训,以确保他们有信心与患者讨论依从性。尽管化学粘附性测试越来越多地被用作确定不粘附性的首选方法,但需要更多的研究来增加化学粘附性测试在更广泛的环境中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Review of the methods to measure non-adherence with a focus on chemical adherence testing

A substantial number of patients with cardiovascular disease do not take their medications as prescribed. This can lead to an increased risk of disease complications, hospitalisations and death. Therefore, it is necessary to determine methods to detect non-adherence in patients accurately to ensure that patients can be identified and engaged with. This will allow adequate support to be provided to these patients to improve adherence rates and thus lead to better disease outcomes.

This review looks at a wide range of methods to establish medication non-adherence. There is a particular focus on chemical adherence testing as this method has gained acceptance in use in many hypertension clinics and has been recommended by European guidelines for use in patients with suspected resistant hypertension.

This review goes onto discuss the use of chemical adherence testing in hypertension clinics currently and also discusses some of the reasons behind non-adherence and provides solutions that can be discussed with the patients to overcome these challenges. The discussion between the clinician and the patient regarding the chemical adherence test result needs to be held in a no-blame environment to ensure that the patient can engage in an open and honest discussion with the clinician. More training is required for clinicians and healthcare professionals to ensure they feel confident to discuss adherence with their patients.

Even though chemical adherence testing is being used increasingly as the first-choice method to determine non-adherence, more research is required to increase uptake of chemical adherence testing in a wider range of settings.

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