{"title":"多发性硬化症的研究与进展","authors":"Áron","doi":"10.36648/2386-5180.21.9.339","DOIUrl":null,"url":null,"abstract":"Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune origin which develops in a genetic susceptible individual triggered by additional environmental factors. In this review we'll provide an update of basic pathogenic concepts. In addition, we'll discuss newly evolving concepts in MS pathogenesis like pathogenic heterogeneity, importance of axonal loss and therefore the role of CD8+ T lymphocytes in tissue injury.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"20 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research and Recent Advancements on Multiple Sclerosis\",\"authors\":\"Áron\",\"doi\":\"10.36648/2386-5180.21.9.339\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune origin which develops in a genetic susceptible individual triggered by additional environmental factors. In this review we'll provide an update of basic pathogenic concepts. In addition, we'll discuss newly evolving concepts in MS pathogenesis like pathogenic heterogeneity, importance of axonal loss and therefore the role of CD8+ T lymphocytes in tissue injury.\",\"PeriodicalId\":8195,\"journal\":{\"name\":\"Annals of Clinical and Laboratory Research\",\"volume\":\"20 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Clinical and Laboratory Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36648/2386-5180.21.9.339\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Clinical and Laboratory Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36648/2386-5180.21.9.339","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Research and Recent Advancements on Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune origin which develops in a genetic susceptible individual triggered by additional environmental factors. In this review we'll provide an update of basic pathogenic concepts. In addition, we'll discuss newly evolving concepts in MS pathogenesis like pathogenic heterogeneity, importance of axonal loss and therefore the role of CD8+ T lymphocytes in tissue injury.
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