中药对血管内皮生长因子的治疗潜力

IF 4.7 3区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Zhejiang University SCIENCE B Pub Date : 2022-05-01 DOI:10.1631/jzus.B2101055

Y. Mao, Lingkai Meng, Huayi Liu, Yuting Lu, Kuo Yang, Guangze Ouyang, Yanran Ban, Shuang Chen

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引用次数: 0

摘要

血管内皮生长因子(Vascular endothelial growth factor, VEGF)是胚胎发育、骨骼生长和生殖功能生理性血管生成的主要调节因子，并参与一系列病理改变。中医药已有2000多年的历史，在临床实践中得到了广泛的应用，而对其作用机制的探索才刚刚开始。本文综述了近年来中药对VEGF影响的研究进展。研究发现，许多中药和方药对VEGF具有调节作用，表明中药作为一种补充和替代疗法具有广阔的前景，为临床应用提供了新的治疗思路，也为中医作用机制的研究提供了理论基础。

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Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor

Vascular endothelial growth factor (VEGF) is the main regulator of physiological angiogenesis during embryonic development, bone growth, and reproductive function, and it also participates in a series of pathological changes. Traditional Chinese medicine (TCM), with a history of more than 2000 years, has been widely used in clinical practice, while the exploration of its mechanisms has only begun. This review summarizes the research of recent years on the influence of TCM on VEGF. It is found that many Chinese medicines and recipes have a regulatory effect on VEGF, indicating that Chinese medicine has broad prospects as a complementary and alternative therapy, providing new treatment ideas for clinical applications and the theoretical basis for research on the mechanisms of TCM.

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来源期刊

Journal of Zhejiang University SCIENCE B 生物-生化与分子生物学

CiteScore

8.70

自引率

13.70%

发文量

2125

审稿时长

3.0 months

期刊介绍： Journal of Zheijang University SCIENCE B - Biomedicine & Biotechnology is an international journal that aims to present the latest development and achievements in scientific research in China and abroad to the world’s scientific community. JZUS-B covers research in Biomedicine and Biotechnology and Biochemistry and topics related to life science subjects, such as Plant and Animal Sciences, Environment and Resource etc.