Study on CD4+T lymphocytes of new Uygur HIV infectors in Urumqi area

Objective: To understand the immune status of new Uygur HIV infectors in Urumqi area by detecting and analyzing CD4⁺T lymphocytes. Methods: Flow cytometry was used to detect absolute counts of CD4⁺T lymphocytes in 92 whole blood samples and the Student’s t test was used for analysis. Results: The mean absolute counts of CD4⁺T lymphocytes of 92 new Uygur HIV infectors was (305.9 ± 168.3) cells/μL. No statistical significances were found in different genders and different transmission routes (P > 0.05). A negative correlation was showed between absolute counts of CD4⁺T lymphocytes and HIV viral load. Conclusions: Two third of the new Uygur HIV infectors in Urumqi area have entered the AIDS phase, so monitoring and antiviral therapy were needed timely. Local government must strengthen publicity and enlarge the monitoring range of CD4⁺T lymphocytes. Early diagnosis and intervention could improve the survival quality of HIV infectors.