Biomatériaux de réparation de la peau et de l'os en chirurgie plastique

Fabricating new tissues requires an interdisciplinary approach that combines developmental, cellular, and molecular biology with clinical medicine, biochemistry, immunology, engineering, and the material sciences. While many researchers are attempting to replicate endogenous structures to create new tissues, numerous barriers must be overcome to create complex, vascularized, patient-specific tissue constructs for replacement and repair. Although multi-step, multi-component tissue fabrication requires an amalgamation of ideas, for clarity we will limit this review to recent developments in the application of natural and synthetic bioabsorbable scaffolds. Herein, we highlight biomaterials potentially useful to plastic and reconstructive surgeons that are currently being used or developed for the replacement and repair of skin and bone.