利用有机材料的三重激发态实现余辉生物应用

IF 10.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Science China Chemistry Pub Date : 2023-10-23 DOI:10.1007/s11426-023-1790-0

Yuanyuan Fan, Qianqian Li, Zhen Li

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引用次数: 0

摘要

具有持久余辉的有机室温磷光材料在生物应用中表现出良好的生物相容性、高信噪比和时间分辨成像特性。此外，它们可以作为缺氧检测探针和光动力治疗剂，用于三重态激子对周围环境中氧气的敏感性。本文综述了利用有机RTP材料进行体外和体内余辉生物成像的最新进展。综述了分子设计策略和分子堆积控制方法，以促进这一新兴的研究领域，重点是磷光发射的高强度、超长寿命和红移波长。

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Afterglow bio-applications by utilizing triplet excited states of organic materials

Organic room temperature phosphorescence (RTP) materials with persistent afterglow exhibit good biocompatibility, high signal to noise ratio and time resolved imaging characteristics in bio-applications. Moreover, they can serve as hypoxia detection probes and photodynamic therapy agents for the sensitivity of triplet excitons toward oxygen in the surroundings. In this review, the recent progress of in vitro and in vivo afterglow bioimaging is presented by utilizing organic RTP materials. The strategies of molecular design and controlling methods of molecular packing were summarized, to prompt this new rising research field, with the emphasis on high intensity, ultralong lifetimes and red-shifted wavelengths of phosphorescence emission.

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来源期刊

Science China Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

14.40

自引率

7.30%

发文量

3787

审稿时长

2.2 months

期刊介绍： Science China Chemistry, co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China and published by Science China Press, publishes high-quality original research in both basic and applied chemistry. Indexed by Science Citation Index, it is a premier academic journal in the field. Categories of articles include: Highlights. Brief summaries and scholarly comments on recent research achievements in any field of chemistry. Perspectives. Concise reports on thelatest chemistry trends of interest to scientists worldwide, including discussions of research breakthroughs and interpretations of important science and funding policies. Reviews. In-depth summaries of representative results and achievements of the past 5–10 years in selected topics based on or closely related to the research expertise of the authors, providing a thorough assessment of the significance, current status, and future research directions of the field.