新技术允许锥束CT在6秒内完成：一项比较图像质量的患者研究。

IF 3.4 3区医学 Q2 ONCOLOGY

Practical Radiation Oncology Pub Date : 2024-05-01 DOI:10.1016/j.prro.2023.10.014

James L. Robar PhD , Amanda Cherpak PhD , Robert Lee MacDonald PhD , Abigail Yashayaeva MSc , David McAloney BSc , Natasha McMaster MSc , Kenny Zhan BSc , Slawa Cwajna MD , Nikhilesh Patil MD , Hannah Dahn MD

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引用次数: 0

摘要

目的：本研究的目的是评估新型锥束CT（CBCT）平台（HyperSightTM，Varian Medical Systems）提供的图像质量，该平台具有增强的重建算法和快速采集时间。将图像质量与用于图像引导的现状CBCT和在CT模拟器（CTsim）上采集的扇形束CT（FBCT）进行比较。方法：在一项临床研究中，招募了30名受试者，在涉及肝、肺、乳腺、腹部、胸壁和胰腺部位的肿瘤的成像和放射治疗过程中，他们使用了深吸气（DIBH）或深呼气屏气（DEBH）。所有受试者在屏息期间在标准图像引导平台（TrueBeam®2.7，Varian Medical Systems）和FBCT CT（CTsim，GE Optima）上使用CBCT进行成像。同时进行屏息（HSBH）和自由呼吸（HSFB）的HyperSight成像。使用量化伪影指数（AI）、图像不均匀性、对比度、对比噪声比（CNR）以及与CTsim的HU差异的指标，对由此获得的四个图像集进行配准和比较。结果：与HSFB和TrueBeam相比，HSBH提供的伪影不那么严重。HSBH图像中伪影的严重程度与CTsim图像中的伪影相似，AI值在统计学上相似。CTsim提供了最佳的图像均匀性，但是与HSFB和TrueBeam相比，HSBH提供了改进的均匀性。与HyperSight成像相比，CTsim显示出更高的对比度，但与TrueBeam相比，HSBH和HSFB成像都显示出更好的CNR特性。HSBH与CTsim的中位HU差异在肌肉/脂肪组织为1 HU，骨骼为12 HU，肺为14 HU。结论：HyperSight系统提供了6秒CBCT采集，与TrueBeam相比，图像伪影显著减少，与CTsim FBCT成像相当。与同一系统上的自由呼吸成像相比，HyperSight屏息成像具有更高的质量。HyperSight屏息成像中的HU中值在肌肉、脂肪、骨骼和肺组织类型的CT模拟成像中的15 HU以内，表明图像数据在自适应工作流程中用于直接剂量计算的效用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Novel Technology Allowing Cone Beam Computed Tomography in 6 Seconds: A Patient Study of Comparative Image Quality

Purpose

The goal of this study was to evaluate the image quality provided by a novel cone beam computed tomography (CBCT) platform (HyperSight, Varian Medical Systems), a platform with enhanced reconstruction algorithms as well as rapid acquisition times. Image quality was compared with both status quo CBCT for image guidance, and to fan beam CT (FBCT) acquired on a CT simulator (CTsim).

Methods and Materials

In a clinical study, 30 individuals were recruited for whom either deep inspiration (DIBH) or deep exhalation breath hold (DEBH) was used during imaging and radiation treatment of tumors involving liver, lung, breast, abdomen, chest wall, and pancreatic sites. All subjects were imaged during breath hold with CBCT on a standard image guidance platform (TrueBeam 2.7, Varian Medical Systems) and FBCT CT (CTsim, GE Optima). HyperSight imaging with both breath hold (HSBH) and free breathing (HSFB) was performed in a single session. The 4 image sets thus acquired were registered and compared using metrics quantifying artifact index, image nonuniformity, contrast, contrast-to-noise ratio, and difference of Hounsfield unit (HU) from CTsim.

Results

HSBH provided less severe artifacts compared with both HSFB and TrueBeam. The severity of artifacts in HSBH images was similar to that in CTsim images, with statistically similar artifact index values. CTsim provided the best image uniformity; however, HSBH provided improved uniformity compared with both HSFB and TrueBeam. CTsim demonstrated elevated contrast compared with HyperSight imaging, but both HSBH and HSFB imaging showed superior contrast-to-noise ratio characteristics compared with TrueBeam. The median HU difference of HSBH from CTsim was within 1 HU for muscle/fat tissue, 12 HU for bone, and 14 HU for lung.

Conclusions

The HyperSight system provides 6-second CBCT acquisition with image artifacts that are significantly reduced compared with TrueBeam and comparable to those in CTsim FBCT imaging. HyperSight breath hold imaging was of higher quality compared with free breathing imaging on the same system. The median HU value in HyperSight breath hold imaging is within 15 HU of that in CTsim imaging for muscle, fat, bone, and lung tissue types, indicating the utility of image data for direct dose calculation in adaptive workflows.

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来源期刊

Practical Radiation Oncology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

6.10%

发文量

177

审稿时长

34 days

期刊介绍： The overarching mission of Practical Radiation Oncology is to improve the quality of radiation oncology practice. PRO''s purpose is to document the state of current practice, providing background for those in training and continuing education for practitioners, through discussion and illustration of new techniques, evaluation of current practices, and publication of case reports. PRO strives to provide its readers content that emphasizes knowledge "with a purpose." The content of PRO includes: Original articles focusing on patient safety, quality measurement, or quality improvement initiatives Original articles focusing on imaging, contouring, target delineation, simulation, treatment planning, immobilization, organ motion, and other practical issues ASTRO guidelines, position papers, and consensus statements Essays that highlight enriching personal experiences in caring for cancer patients and their families.