用于心血管护理的低密度脂蛋白胆固醇、非高密度脂蛋白蛋白胆固醇和载脂蛋白B。

IF 2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Current Opinion in Cardiology Pub Date : 2024-01-01 Epub Date: 2023-11-06 DOI:10.1097/HCO.0000000000001100
Selin Bilgic, Allan D Sniderman
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引用次数: 0

摘要

综述目的:一些专家和共识团体继续认为,载脂蛋白B(apoB)不应广泛引入临床护理。但是,目前的临床护理方法往往并不成功。我们认为,这种失败的一个重要原因是,传统的方法限制了专业临床医生的能力,而且过于复杂、令人困惑和矛盾,初级保健医生无法在实践中有效应用。最近的发现:有四个主要的原因,apoB应该定期测量在临床护理。首先,apoB是比LDL-C或非HDL-C更准确的心血管风险标志物。其次,apoB的测量是标准化的,而LDL-C和非HDL-C的测量则不是标准化的。第三,使用apoB和传统的脂质组,可以简单准确地区分所有的脂质表型。这将提高专家的护理水平。第四,apoB作为评估治疗成功与否的单一指标,将简化初级保健医生的护理过程。摘要:通过将apoB广泛引入临床护理,专家和初级保健医生的护理过程都将得到改善,这将改善护理结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol and apolipoprotein B for cardiovascular care.

Purpose of review: Some experts and consensus groups continue to argue that apolipoprotein B (apoB) should not be introduced broadly into clinical care. But, too often, the present approach to clinical care is not succeeding. An important reason for this failure, we believe, is that the conventional approach limits what the expert clinician can accomplish and is too complex, confusing, and contradictory for primary care physicians to apply effectively in their practise.

Recent findings: There are four major reasons that apoB should be measured routinely in clinical care. First, apoB is a more accurate marker of cardiovascular risk than LDL-C or non-HDL-C. Second, the measurement of apoB is standardized whereas the measurements of LDL-C and non-HDL-C are not. Third, with apoB and a conventional lipid panel, all the lipid phenotypes can be simply and accurately distinguished. This will improve the care of the expert. Fourth, apoB, as the single measure to evaluate the success of therapy, would simplify the process of care for primary care physicians.

Summary: By introducing apoB broadly into clinical care, the process of care will be improved for both the expert and the primary care physician, and this will improve the outcomes of care.

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来源期刊
Current Opinion in Cardiology
Current Opinion in Cardiology 医学-心血管系统
CiteScore
4.20
自引率
4.30%
发文量
78
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Cardiology is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With fourteen disciplines published across the year – including arrhythmias, molecular genetics, HDL cholesterol and clinical trials – every issue also contains annotated reference detailing the merits of the most important papers.
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