Sigma-1受体正电子发射断层扫描/磁共振成像实用指南：一种新的临床分子成像方法，用于识别慢性疼痛患者的外周疼痛发生器。

IF 0.9 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI:10.1055/s-0043-1775744

Bin Shen, Daehyun Yoon, Jessa Castillo, Sandip Biswal

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引用次数: 0

摘要

准确识别慢性疼痛患者的外周疼痛发生器仍然是现代医学的一大挑战。由于诊断测试非常有限，疼痛疗法匮乏，全世界数百万患者无休止地遭受难以控制的衰弱性疼痛。为了帮助这些患者，我们开发了一种新的临床分子成像方法，在其早期阶段，已经证明使用sigma-1受体的成像生物标志物和正电子发射断层扫描/磁共振成像可以准确识别疼痛产生的确切部位。我们希望本文中对这项工作的描述能够帮助其他人在各自的机构开始他们自己的疼痛成像项目。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Practical Guide to Sigma-1 Receptor Positron Emission Tomography/Magnetic Resonance Imaging: A New Clinical Molecular Imaging Method to Identify Peripheral Pain Generators in Patients with Chronic Pain.

Accurately identifying the peripheral pain generator in patients with chronic pain remains a major challenge for modern medicine. Millions of patients around the world suffer endlessly from difficult-to-manage debilitating pain because of very limited diagnostic tests and a paucity of pain therapies. To help these patients, we have developed a novel clinical molecular imaging approach, and, in its early stages, it has been shown to accurately identify the exact site of pain generation using an imaging biomarker for the sigma-1 receptor and positron emission tomography/magnetic resonance imaging. We hope the description of the work in this article can help others begin their own pain imaging programs at their respective institutions.

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来源期刊

Seminars in Musculoskeletal Radiology 医学-核医学

CiteScore

2.50

自引率

7.10%

发文量

112

审稿时长

>12 weeks

期刊介绍： Seminars in Musculoskeletal Radiology is a review journal that is devoted to musculoskeletal and associated imaging techniques. The journal''s topical issues encompass a broad spectrum of radiological imaging including body MRI imaging, cross sectional radiology, ultrasound and biomechanics. The journal also covers advanced imaging techniques of metabolic bone disease and other areas like the foot and ankle, wrist, spine and other extremities. The journal''s content is suitable for both the practicing radiologist as well as residents in training.